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A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity
(Nature Communications, 2024-02-05)Here we report the characterization of 17T2, a SARS-CoV-2 pan-neutralizing human monoclonal antibody isolated from a COVID-19 convalescent individual infected during the first pandemic wave. 17T2 is a ... -
A multilevel investigation supported by multivariate analysis for tomato product formulation
(European Food Research and Technology, 2021-06-18)Industrial processing of tomato includes its cutting and mincing, thermal treatments, and the addition of ingredients, which might induce changes in physicochemical properties of the final products. In ... -
A multiplier peroxiporin signal transduction pathway powers piscine spermatozoa
(Proceedings of the National Academy of Sciences (PNAS), 2021-03-09)The primary task of a spermatozoon is to deliver its nuclear payload to the egg to form the next-generation zygote. With polyandry repeatedly evolving in the animal kingdom, however, sperm competition ... -
A mutation in the melon Vacuolar Protein Sorting 41prevents systemic infection of Cucumber mosaic virus
(Scientific Reports, 2017-09-05)In the melon exotic accession PI 161375, the gene cmv1, confers recessive resistance to Cucumber mosaic virus (CMV) strains of subgroup II. cmv1 prevents the systemic infection by restricting the ... -
A mycobacterial disease is associated with the silent mass mortality of the pen shell Pinna nobilis along the Tyrrhenian coastline of Italy
(Scientific Reports, 2019-02-25)Disease is an increasing threat for marine bivalves worldwide. Recently, a mass mortality event (MME) impacting the bivalve Pinna nobilis was detected across a wide geographical area of the Spanish ... -
A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
(BMC Veterinary Research, 2020-01-14)Background: Virus neutralization test (VNT) is widely used for serological survey of classical swine fever (CSF) and efficacy evaluation of CSF vaccines. However, VNT is a time consuming procedure that ... -
A new approach to obtain pure and active proteins from Lactococcus lactis protein aggregates
(Scientific Reports, 2018-09-17)The production of pure and soluble proteins is a complex, protein-dependent and time-consuming process, in particular for those prone-to-aggregate and/or difcult-to-purify. Although Escherichia coli ... -
A new expanded modelling approach for investigating the bioprotective capacity of Latilactobacillus sakei CTC494 against Listeria monocytogenes in ready-to-eat fish products
(Food Research International, 2021-06-18)Understanding the role of food-related factors on the efficacy of protective cultures is essential to attain optimal results for developing biopreservation-based strategies. The aim of this work was to ... -
A new generation of recombinant polypeptides combines multiple protein domains for effective antimicrobial activity
(Microbial Cell Factories, 2020-06-05)Background Although most of antimicrobial peptides (AMPs), being relatively short, are produced by chemical synthesis, several AMPs have been produced using recombinant technology. However, AMPs could ... -
A Novel Bacterial 6-Phytase Improves Growth Performance, Tibia Mineralization and Precaecal Digestibility of Phosphorus in Broilers: Data from Four Independent Performance Trials
(Agriculture, 2023-07-27)A series of four broiler performance studies were conducted in different facilities to investigate the efficacy of a novel bacterial 6-phytase added at 500 FTU/kg diet on growth performance, bone ... -
A Novel Bacterial 6-Phytase Improves Productive Performance, Precaecal Digestibility of Phosphorus, and Bone Mineralization in Laying Hens Fed a Corn-Soybean Meal Diet Low in Calcium and Available Phosphorus
(Journal of Poultry Science, 2023-08-05)Exogenous phytases are commonly added to low-phosphorus and low-calcium diets to improve P availability and reduce P excretion by poultry. This study investigated the effect of supplementation with a ... -
A Novel E2 Glycoprotein Subunit Marker Vaccine Produced in Plant Is Able to Prevent Classical Swine Fever Virus Vertical Transmission after Double Vaccination
(Vaccines, 2021-04-22)The efficacy of a novel subunit vaccine candidate, based in the CSFV E2 glycoprotein produced in plants to prevent classical swine fever virus (CSFV) vertical transmission, was evaluated. A Nicotiana ... -
A Novel Generation of Tailored Antimicrobial Drugs Based on Recombinant Multidomain Proteins
(Pharmaceutics, 2023-03-26)Antibiotic resistance has exponentially increased during the last years. It is necessary to develop new antimicrobial drugs to prevent and treat infectious diseases caused by multidrug- or extensively-drug ... -
A novel glucuronoxylan hydrolase produced by fermentation is safe as feed additive: toxicology and tolerance in broiler chickens
(Regulatory Toxicology and Pharmacology, 2018-09-25)The current study presents a safety evaluation of a novel glucuronoxylan hydrolase (EC 3.2.1.136) from Bacillus subtilis produced in Bacillus licheniformis. The glucuronoxylan hydrolase preparation did ... -
A novel introgression line collection to unravel the genetics of climacteric ripening and fruit quality in melon
(Scientific Reports, 2021-05-31)Introgression lines are valuable germplasm for scientists and breeders, since they ease genetic studies such as QTL interactions and positional cloning as well as the introduction of favorable alleles ... -
A novel optical sensor system for the automatic classification of mosquitoes by genus and sex with high levels of accuracy
(Parasites and Vectors, 2022-06-06)Background: Every year, more than 700,000 people die from vector-borne diseases, mainly transmitted by mosqui‑ toes. Vector surveillance plays a major role in the control of these diseases and requires ... -
A Novel Real Time PCR Method for the Detection and Quantification of Didymella pinodella in Symptomatic and Asymptomatic Plant Hosts
(Journal of Fungi (JoF), 2021-12-31)Didymella pinodella is the major pathogen of the pea root rot complex in Europe. This wide host range pathogen often asymptomatically colonizes its hosts, making the control strategies challenging. We ... -
A pegada hídrica da produção de carne de bovino na Catalunha
(Voz do Campo, 2023, 270, Maio, 72-73, 2023-05) -
A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome
(Theriogenology, 2020-08-15)The microbiome plays a key role in homeostasis and health and it has been also linked to fertility and semen quality in several animal species including swine. Despite the more than likely importance ... -
A pilot study about on-farm assessment of health and welfare in rabbits kept in different housing systems
(Frontiers in Veterinary Science, 2022-08-11)This pilot study tested an on-farm protocol based on resource, management, and animal-based measures to evaluate the on-farm health and welfare of rabbits kept in four different housing systems. In ...