Now showing items 1-8 of 8

    • Animal models for COVID-19 

      Muñoz-Fontela, César; Dowling, William E.; Funnell, Simon G. P.; Gsell, Pierre-S.; Riveros-Balta, A. Ximena; Albrecht, Randy A.; Andersen, Hanne; Baric, Ralph S.; Carroll, Miles W.; Cavaleri, Marco; Qin, Chuan; Crozier, Ian; Dallmeier, Kai; de Waal, Leon; de Wit, Emmie; Delang, Leen; Dohm, Erik; Duprex, W. Paul; Falzarano, Darryl; Finch, Courtney L.; Frieman, Matthew B.; Graham, Barney S.; Gralinski, Lisa E.; Guilfoyle, Kate; Haagmans, Bart L.; Hamilton, Geraldine A.; Hartman, Amy L.; Herfst, Sander; Kaptein, Suzanne J. F.; Klimstra, William B.; Knezevic, Ivana; Krause, Philip R.; Kuhn, Jens H.; Le Grand, Roger; Lewis, Mark G.; Liu, Wen-Chun; Maisonnasse, Pauline; McElroy, Anita K.; Munster, Vincent; Oreshkova, Nadia; Rasmussen, Angela L.; Rocha-Pereira, Joana; Rockx, Barry; Rodríguez, Estefanía; Rogers, Thomas F.; Salguero, Francisco J.; Schotsaert, Michael; Stittelaar, Koert J.; Thibaut, Hendrik Jan; Tseng, Chien-Te; Vergara-Alert, Júlia; Beer, Martin; Brasel, Trevor; Chan, Jasper F. W.; García-Sastre, Adolfo; Neyts, Johan; Perlman, Stanley; Reed, Douglas S.; Richt, Juergen A.; Roy, Chad J.; Segalés, Joaquim; Vasan, Seshadri S.; Henao-Restrepo, Ana María; Barouch, Dan H. (Nature, 2020-09-23) Sanitat Animal
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel ...
    • Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein 

      Rodon, Jordi; Okba, Nisreen M. A.; Te, Nigeer; van Dieren, Brenda; Bosch, Berend-Jan; Bensaid, Albert; Segalés, Joaquim; Haagmans, Bart L.; Vergara-Alert, Júlia (Emerging Microbes and Infections, 2019-11-12) Sanitat Animal
      The ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks pose a worldwide public health threat. Blocking MERS-CoV zoonotic transmission from dromedary camels, the animal reservoir, ...
    • Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection 

      Stalin Raj, V.; Okba, Nisreen M. A.; Gutierrez-Alvarez, Javier; Drabek, Dubravka; van Dieren, Brenda; Widagdo, W.; Lamers, Mart M.; Widjaja, Ivy; Fernandez-Delgado, Raul; Sola, Isabel; Bensaid, Albert; Koopmans, Marion P.; Segalés, Joaquim; Osterhaus, Albert D. M. E.; Jan Bosch, Berend; Enjuanes, Luis; Haagmans, Bart L. (Science Advances, 2018-08-08) Sanitat Animal
      Middle East respiratory syndrome coronavirus (MERS-CoV) continues to cause outbreaks in humans as a result of spillover events from dromedaries. In contrast to humans, MERS-CoV–exposed dromedaries develop ...
    • Co‐localization of Middle East respiratory syndrome coronavirus (MERS‐CoV) and dipeptidyl peptidase‐4 in the respiratory tract and lymphoid tissues of pigs and llamas 

      Te, Nigeer; Vergara‐Alert, Júlia; Lehmbecker, Annika; Pérez, Mónica; Haagmans, Bart L.; Baumgärtner, Wolfgang; Bensaid, Albert; Segalés, Joaquim (Transboundary and Emerging Diseases, 2018-12-06) Sanitat Animal
      This study investigated the co‐localization of the Middle East respiratory syndrome coronavirus (MERS‐CoV) and its receptor dipeptidyl peptidase‐4 (DPP4) by immunohistochemistry (IHC) across respiratory ...
    • Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4 

      Haverkamp, Ann-Kathrin; Lehmbecker, Annika; Spitzbarth, Ingo; Widagdo, Widagdo; Haagmans, Bart L.; Segalés, Joaquim; Vergara-Alert, Julia; Bensaid, Albert; van den Brand, Judith M. A.; Osterhaus, Albert D. M. E.; Baumgärtner, Wolfgang (Scientific Reports, 2018-06-27) Sanitat Animal
      Middle East respiratory syndrome (MERS) represents an important respiratory disease accompanied by lethal outcome in one-third of human patients. Recent data indicate that dromedaries represent an ...
    • Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain 

      Rodon, Jordi; Mykytyn, Anna Z.; Te, Nigeer; Okba, Nisreen M.A.; Lamers, Mart M.; Pailler-García, Lola; Cantero, Guillermo; Albulescu, Irina; Bosch, Berend-Jan; Peiris, Malik; Bensaid, Albert; Vergara-Alert, Júlia; Haagmans, Bart L.; Segalés, Joaquim (Emerging Infectious Diseases, 2023-02-07) Sanitat Animal
      Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended ...
    • Middle East respiratory syndrome coronavirus infection in camelids 

      Te, Nigeer; Ciurkiewicz, Malgorzata; van den Brand, Judith M. A.; Rodon, Jordi; Haverkamp, Ann-Kathrin; Vergara-Alert, Júlia; Bensaid, Albert; Haagmans, Bart L.; Baumgartner, Wolfgang; Segalés, Joaquim (Veterinary Pathology, 2022-01-08) Sanitat Animal
      Middle East respiratory syndrome coronavirus (MERS-CoV) is the cause of a severe respiratory disease with a high case fatality rate in humans. Since its emergence in mid-2012, 2578 laboratory-confirmed ...
    • Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas 

      Rodon, Jordi; Mykytyn, Anna Z.; Cantero, Guillermo; Albulescu, Irina C.; Bosch, Berend-Jan; Brix, Alexander; Audonnet, Jean-Christophe; Bensaid, Albert; Vergara-Alert, Júlia; Haagmans, Bart L.; Segalés, Joaquim (One Health Outlook, 2022-06-24) Sanitat Animal
      Ongoing outbreaks of Middle East respiratory syndrome coronavirus (MERS-CoV) continue posing a global health threat. Vaccination of livestock reservoir species is a recommended strategy to prevent spread ...