Risk factors associated withStreptococcus suiscases on pigfarms in Spain
View/Open
Author
Franco-Martínez, Lorena
Cerón, José Joaquín
Casal, Jordi
Publication date
2023-06-03ISSN
0042-4900
Abstract
Background
Streptococcus suis can cause meningitis, polyarthritis and acute death in piglets. However, the risk factors associated with S. suis infection remain incompletely understood. Therefore, a longitudinal study was carried out, in which six batches from two Spanish pig farms with S. suis problems were repeatedly examined to determine possible risk factors.
Methods
A prospective case–control study was conducted, and potential risk factors were evaluated using mixed-effects logistic regression models. The explanatory variables included: (a) concomitant pathogens; (b) biomarkers associated with stress, inflammation and oxidative status; (c) farm environmental factors; and (d) parity and S. suis presence in sows. Three models were built to study the effect of these variables, including two to assess the risk factors involved in the subsequent development of disease.
Results
Risk factors for S. suis-associated disease included porcine reproductive and respiratory syndrome virus co-infection at weaning (odds ratio [OR] = 6.69), sow parity (OR = 0.71), haptoglobin level before weaning (OR = 1.01), relative humidity (OR = 1.11) and temperature (OR = 0.13).
Limitations
Laboratory diagnosis was done at the batch level, with individual diagnosis based on clinical signs only.
Conclusions
This study confirms the multifactorial nature of S. suis-associated disease, with both environmental factors and factors related to the host involved in disease development. Controlling these factors may, therefore, help prevent the appearance of disease.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
10
Publisher
Wiley
Is part of
Veterinary Record
Citation
Neila‐Ibáñez, Carlos, Sebastián Napp, Lola Pailler‐García, Lorena Franco‐Martínez, José Joaquín Cerón, Virginia Aragon, and Jordi Casal. 2023. Veterinary Record 193 (5). doi:10.1002/vetr.3056.
Grant agreement number
EC/H2020/727966/EU/Program for Innovative Global Prevention of Streptococcus suis/PIGSs
Program
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2555]
The following license files are associated with this item:
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/