Impact of genetic diversity and antibiotic-resistance of Salmonella isolated from feral cats: One Health approach
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Author
Marin, C.
Rosario, I.
Lorenzo-Rebenaque, L.
Vega, S.
Padilla, D.
Real, F.
Rodriguez-Ponce, E.
Acosta-Hernández, B.
Publication date
2023-08-29ISSN
0147-9571
Abstract
Free-living cats usually live in colonies in urban areas, especially close to parks and neighbourhoods where
people feed them without any sanitary control. This can pose a human, animal and environmental health concern
due to the close contact between uncontrolled colonies, the population and other domestic and/or wild animals.
Thus, this study aimed to assess the genetic diversity and antimicrobial resistance (AMR) among Salmonella
enterica subsp. enterica strains isolated from feral cats in a previous epidemiological study in the Gran Canaria
island (Spain). A total of nineteen Salmonella isolates were obtained from November 2018 to January 2019 in a
Salmonella epidemiological study in feral cats. All isolates obtained were genotyped by pulsed-field gel electrophoresis (PGFE) and were tested for antimicrobial susceptibility, in accordance with Decision 2013/652/EU.
PFGE analysis revealed isolates clustering by serovar, with identical clones for serovars Bredeney and Grancanaria, while differing pulsotypes were observed for serovars Florida (88.89 % similarity) and Nima (83.23 %
similarity). All but two isolates were resistant to at least one antimicrobial. The results obtained demonstrate that
feral cats in the region investigated are a reservoir of Salmonella strains resistant to gentamicin (94.1 %) and of
the critically important antimicrobial tigecycline (23.5 %). Hence, they could excrete AMR strains through their
faeces and contaminate the environment, favoring the spread of such bacteria to cohabiting pets. Moreover, this
widespread presence of AMR Salmonella clones across various serovars highlights the urgent need to implement
efficient antimicrobial stewardship and control programs by the local governments due to the ongoing need to
protect human and animal health under a One Health concept.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
18
Publisher
Elsevier
Is part of
Comparative Immunology, Microbiology and Infectious Diseases
Citation
Marín, Clara, Marta Cerdà‐Cuéllar, Inmaculada Rosario, Laura Lorenzo-Rebenaque, Santiago Vega, A. Manzanares, Daniel Padilla, Fernando Real, Eligia Rodríguez-Ponce, and Begoña Acosta-Hernández. 2023. “Impact of Genetic Diversity and Antibiotic-Resistance of Salmonella Isolated from Feral Cats: One Health Approach.” Comparative Immunology Microbiology and Infectious Diseases 101: 102043. doi:10.1016/j.cimid.2023.102043.
Program
Sanitat Animal
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