Atypical disseminated histiocytic sarcoma in a 7-month-old dog: a case report
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Author
Garcia-Torres, Maria
Serrano Muñoz, Bárbara
Mallol, Clàudia
Sanz, Alba
López, María C.
Roura, Xavier
Publication date
2024-01-19ISSN
0275-6382
Abstract
A 7-month-old intact female bearded collie dog was admitted after a two-week history of
progressive cough, inappetence, and lethargy, with no response to previous treatment with
doxycycline and steroids. Mild attenuation of lung sounds in the right middle hemithorax was
the only abnormality detected on physical examination. Abdominal ultrasound and thoracic
radiographs were performed and revealed multifocally distributed nodules and masses, wellcircumscribed and of variable size in the kidneys and pulmonary parenchyma. Ultrasoundguided fine needle aspirates of the renal and pulmonary masses were taken. A cytologic
evaluation of these lesions pointed towards a malignant mesenchymal neoplasia. Euthanasia
was elected due to the poor prognosis and rapid progression. The post-mortem histopathology,
a positive result to IBA1 immunoperoxidase staining, and a lack of detection of infectious agents,
and negative E-cadherin immunostaining enabled the final diagnosis of a disseminated
histiocytic sarcoma. We report an atypical form, both in breed and age, of canine disseminated
histiocytic sarcoma. While all breeds can be affected, there is a clear predisposition in some, and
no cases have been previously described in bearded collies. Moreover, to the authors’
knowledge, this is the youngest dog with this histiocytic disorder described to date.
Disseminated histiocytic sarcoma should be considered as a differential diagnosis of
multinodular tumors in dogs, regardless of the anatomic location and age of the dogs, even in
puppies.
Document Type
Article
Document version
Accepted version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
21
Publisher
Wiley
Is part of
Veterinary Clinical Pathology
Citation
Garcia‐Torres, Maria, Bárbara Serrano Muñoz, Joaquím Segalés, Clàudia Mallol, A. Marco Sanz, María Cristina Sánchez López, and Xavier Roura. 2024. “Atypical Disseminated Histiocytic Sarcoma in a 7‐month‐old Dog: A Case Report.” Veterinary Clinical Pathology, January. doi:10.1111/vcp.13328.
Program
Sanitat Animal
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- ARTICLES CIENTÍFICS [2555]
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Copyright © American Society for Veterinary Clinical Pathology