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    • Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies 

      Eraña, Hasier; Charco, Jorge M.; Di Bar, Michele A.; Díaz-Domínguez, Carlos M.; López-Moreno, Rafael; Vidal, Enric; González-Miranda, Ezequiel; Pérez-Castro, Miguel A.; García-Martínez, Sandra; Bravo, Susana; Fernández-Borges, Natalia; Geijo, Mariví; D’Agostino, Claudia; Garrido, Joseba; Bian, Jifeng; König, Anna; Uluca-Yazgi, Boran; Sabate, Raimon; Khaychuk, Vadim; Vanni, Ilaria; Telling, Glenn C.; Heise, Henrike; Nonno, Romolo; Requena, Jesús R.; Castilla, Joaquín (PLoS Pathogens, 2019-10-23) Sanitat Animal
      The resolution of the three-dimensional structure of infectious prions at the atomic level is pivotal to understand the pathobiology of Transmissible Spongiform Encephalopathies (TSE), but has been long ...