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Now showing items 11-20 of 43
An anti-SARS-CoV-2 metabolite is reduced in diabetes
(Nature Research, 2022-05-09)
A glucose-like metabolite, which is reduced in the serum of diabetic patients, inhibits the entry of SARS-CoV-2 into key cellular targets. The work led by Cheng and colleagues provides a molecular ...
Exposure to a Low Pathogenic A/H7N2 Virus in Chickens Protects against Highly Pathogenic A/H7N1 Virus but Not against Subsequent Infection with A/H5N1
(Public Library of Science, 2013-03-04)
Recent evidences have demonstrated that the presence of low pathogenic avian influenza viruses (LPAIV) may play an important role in host ecology and transmission of avian influenza viruses (AIV). While ...
Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain
(Centers for Disease Control and Prevention, 2023-02-07)
Middle East respiratory syndrome coronavirus (MERS-CoV) clade B viruses are found in camelids and humans in the Middle East, but clade C viruses are not. We provide experimental evidence for extended ...
Monitoring Natural SARS-CoV-2 Infection in Lions (Panthera leo) at the Barcelona Zoo: Viral Dynamics and Host Responses
(MDPI, 2021-08-25)
To date, no evidence supports the fact that animals play a role in the epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus infectious ...
Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection
(Public Library of Science, 2021-05-24)
While MERS-CoV (Middle East respiratory syndrome Coronavirus) provokes a lethal disease in humans, camelids, the main virus reservoir, are asymptomatic carriers, suggesting a crucial role for innate ...
Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins
(Future Medicine, 2020-09-09)
Background: Cross-reactivity against human coronaviruses with Flebogamma® DIF and Gamunex®-C, two available intravenous immunoglobulins (IVIG), has been reported. In this study, these IVIG were tested ...
Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection
(Cell Press, 2022-01-24)
To understand the determinants of long-term immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the concurrent impact of vaccination and emerging variants, we follow a ...
Zoonotic diseases: Can the transmission of pathogens between animals and humans be controlled?
(Universitat de Valencia, 2023-02-23)
After being associated with more than six million deaths so far, the Covid-19 pandemic is one of the worst diseases of animal origin known to date. Other zoonotic diseases such as severe acute respiratory ...
Kinetics of immune responses elicited after three mRNA COVID-19 vaccine doses in predominantly antibody-deficient individuals
(Cell Press, 2022-10-28)
Mass vaccination campaigns reduced COVID-19 incidence and severity. Here, we evaluated the immune responses developed in SARS-CoV-2-uninfected patients with predominantly antibody-deficiencies (PAD) ...
Protective effect of a polyvalent influenza DNA vaccine in pigs
(Elsevier, 2017-11-23)
Background: Influenza A virus in swine herds represents a major problem for the swine industry and poses a
constant threat for the emergence of novel pandemic viruses and the development of more effective ...