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Evaluation of Toxicity Equivalency Factors of Tetrodotoxin Analogues with a Neuro-2a Cell-Based Assay and Application to Puffer Fish from Greece
(MDPI, 2023-07-29)
Tetrodotoxin (TTX) is a potent marine neurotoxin involved in poisoning cases, especially through the consumption of puffer fish. Knowledge of the toxicity equivalency factors (TEFs) of TTX analogues is ...
Cyclodextrin polymers as passive sampling materials for lipophilic marine toxins in Prorocentrum lima cultures and a Dinophysis sacculus bloom in the NW Mediterranean Sea
(Elsevier, 2021-07-09)
Cyclodextrins, cyclic oligomers that form a conical structure with an internal cavity, are proposed as new and sustainable materials for passive sampling of lipophilic marine toxins. Two applicability ...
Bioaccessibility of lipophilic and hydrophilic marine biotoxins in seafood: An in vitro digestion approach
(Elsevier, 2019-04-28)
This study aimed to assess the bioaccessibility of different marine biotoxins in naturally contaminated shellfish and fish gonads using an in vitro digestion methodology. In general, hydrophilic toxins ...
Detection of tetrodotoxins in juvenile pufferfish Lagocephalus sceleratus (Gmelin, 1789) from the North Aegean Sea (Greece) by an electrochemical magnetic bead-based immunosensing tool
(Elsevier, 2019-03-29)
Two small Lagocephalus sceleratus juveniles were captured in picarel targeting catches from North Aegean Sea (Greece) in the autumn of 2017. An electrochemical immunosensing tool using magnetic beads ...
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean
(Nature Research, 2017-08-15)
Severe food poisoning events after the consumption of sharks have been reported since the 1940s;
however, there has been no clear understanding of their cause. Herein, we report for the frst time ...
Identification of New CTX Analogues in Fish from the Madeira and Selvagens Archipelagos by Neuro-2a CBA and LC-HRMS
(MDPI, 2022-03-29)
Ciguatera Poisoning (CP) is caused by consumption of fish or invertebrates contaminated with ciguatoxins (CTXs). Presently CP is a public concern in some temperate regions, such as Macaronesia (North-Eastern ...
Addressing the analytical challenges for the detection of ciguatoxins using an electrochemical biosensor
(American Chemical Society, 2020-03-05)
The importance of ciguatoxins (CTXs) in seafood safety and their emerging occurrence in locations far away from tropical areas highlight the need for simple and low-cost methods for the sensitive and ...
A fast magnetic bead-based colorimetric immunoassay for the detection of tetrodotoxins in shellfish
(Elsevier, 2020-04-05)
Tetrodotoxin (TTX) is a potent neurotoxin responsible for many food poisoning incidents and some fatalities. Although mainly associated with the consumption of pufferfish, in recent years, TTX has been ...
Self-assembled monolayer-based immunoassays for okadaic acid detection in seawater as monitoring tools
(Elsevier, 2017-11-14)
Rapid and cost-effective methods to monitor the presence of diarrhetic shellfish poisoning (DSP) toxins in seawater samples in an easy and reliable manner are required to protect human health and avoid ...
Development and validation of a maleimide-based enzyme-linked immunosorbent assay for the detection of tetrodotoxin in oysters and mussels
(Elsevier, 2017-08-18)
The recent detection of tetrodotoxins (TTXs) in puffer fish and shellfish in Europe highlights the necessity to monitor the levels of TTXs in seafood by rapid, specific, sensitive and reliable methods ...