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Bacterial inclusion bodies are industrially exploitable amyloids
(Oxford University Press, 2018-10-24)
Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein ...
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
(MDPI, 2024-01-26)
Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by ...
Exploring the use of leucine zippers for the generation of a new class of inclusion bodies for pharma and biotechnological applications
(BMC, 2020-09-04)
Background
Inclusion bodies (IBs) are biologically active protein aggregates forming natural nanoparticles with a high stability and a slow-release behavior. Because of their nature, IBs have been ...