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Molecular phenomics of a high-calorie diet-induced porcine model of prepubertal obesity 

Jové, Mariona; Tibau, Joan; Serrano, José CE; Berdún, Rebeca; Rodríguez-Palmero, María; Font-i-Furnols, Maria; Cassanyé, Anna; Rodriguez-Mortera, Reyna; Sol, Joaquim; Rassendren, Helene; Fàbrega, Emma; Crescenti, Anna; Castell, Anna; Sabater, Mònica; Ortega, Francisco J.; Martin-Gari, Meritxell; Quintanilla, Raquel; Puigjaner, Joaquim; Moreno, Jose Antonio; Prat, Joan; Arola, Lluis; Fernández-Real, Josep Manuel; Pamplona, Reinald; Portero-Otin, Manuel (The Journal of Nutritional Biochemistry, 2020-04-24)
As obesity incidence is alarmingly rising among young individuals, we aimed to characterize an experimental model of this situation, considering the similarity between human and porcine physiology. For ...
 

Effects of breed‐production system on collagen, textural, and sensory traits of 10 European beef cattle breeds 

Panea, Begoña; Olleta, José Luis; Sañudo, Carlos; Campo, María del Mar; Oliver, María Angels; Gispert, Marina; Serra, Xavier; Renand, Gilles; Oliván, María del Carmen; Jabet, Sylvie; García, Susana; López, Montaña; Izquierdo, Mercedes; García‐Cachán, María Dolores; Quintanilla, Raquel; Piedrafita, Jesús (Journal of Texture Studies, 2018-06-23)
In the current study the collagen, texture, and sensory characteristics of meat from 712 yearling males of 10 local Spanish and French beef breeds raised in their typical production systems were described. ...
 

Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach 

Mármol-Sánchez, Emilio; Cirera, Susanna; Quintanilla, Raquel; Pla, Albert; Amills, Marcel (Genomics, 2019-12-06)
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we ...
 

Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles 

Cardoso, Tainã Figueiredo; Quintanilla, Raquel; Castelló, Anna; González-Prendes, Rayner; Amills, Marcel; Cánovas, Ángela (BMC Genomics, 2018-02-14)
Background: The identification of genes differentially expressed in the skeletal muscle of pigs displaying distinct growth and fatness profiles might contribute to identify the genetic factors that ...
 

Diversity across major and candidate genes in European local pig breeds 

Muñoz, María; Bozzi, Riccardo; García, Fabián; Núñez, Yolanda; Geraci, Claudia; Crovetti, Alessandro; García-Casco, Juan; Alves, Estefania; Skrlep, Martin; Charneca, Rui; Martins, Jose M.; Quintanilla, Raquel; Tibau, Joan; Kusec, Goran; Djurkin-Kusec, Ivona; Mercat, Marie J.; Riquet, Juliette; Estelle, Jordi; Zimmer, Christoph; Razmaite, Violeta; Araujo, Jose P.; Radović, Čedomir; Savić, Radomir; Karolyi, Danijel; Gallo, Maurizio; Čandek-Potokar, Marjeta; Fontanesi, Luca; Fernández, Ana I.; Óvilo, Cristina (PLoS ONE, 2018-11-20)
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...
 

Polymorphisms of the cryptochrome 2 and mitoguardin 2 genes are associated with the variation of lipid-related traits in Duroc pigs 

Mármol-Sánchez, Emilio; Quintanilla, Raquel; Cardoso, Taina F.; Jordana Vidal, Jordi; Amills, Marcel (Scientific Reports, 2019-06-21)
The genetic factors determining the phenotypic variation of porcine fatness phenotypes are still largely unknown. We investigated whether the polymorphism of eight genes (MIGA2, CRY2, NPAS2, CIART, ARNTL2, ...
 

Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity 

Ballester, Maria; Quintanilla, Raquel; Ortega, Francisco J.; Serrano, José C. E.; Cassanyé, Anna; Rodríguez-Palmero, Maria; Moreno-Muñoz, José A.; Portero-Otin, Manuel; Tibau, Joan (Scientific Reports, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
 

Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply 

Mármol-Sánchez, Emilio; Ramayo-Caldas, Yuliaxis; Quintanilla, Raquel; Cardoso, Tainã Figueiredo; González-Prendes, Rayner; Tibau, Joan; Amills, Marcel (Journal of Animal Science and Biotechnology, 2020-01-17)
Background The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
 

Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles 

González-Prendes, Rayner; Quintanilla, Raquel; Mármol-Sánchez, Emilio; Pena, Ramona N.; Ballester, Maria; Cardoso, Tainã Figueiredo; Manunza, Arianna; Casellas, Joaquim; Cánovas, Ángela; Díaz, Isabel; Noguera, José Luis; Castelló, Anna; Mercadé, Anna; Amills, Marcel (BMC Genomics, 2019-03-04)
Background Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...
 

Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs 

Piles, Miriam; Fernandez‑Lozano, Carlos; Velasco‑Galilea, María; González‑Rodríguez, Olga; Sánchez, Juan Pablo; Torrallardona, David; Ballester, Maria; Quintanilla, Raquel (Genetics Selection Evolution, 2019-03-13)
Background: To date, the molecular mechanisms that underlie residual feed intake (RFI) in pigs are unknown. Results from diferent genome‑wide association studies and gene expression analyses are not ...
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Quintanilla, Raquel (19)
Amills, Marcel (9)Ballester, Maria (9)Mármol-Sánchez, Emilio (7)González-Prendes, Rayner (6)Ramayo-Caldas, Yuliaxis (6)Tibau, Joan (6)Cardoso, Tainã Figueiredo (4)Castelló, Anna (4)Cánovas, Ángela (3)... Show moreSubject619 (9)636 (6)575 (2)59 (2)63 (2)636 - Explotació i cria d'animals. Cria del bestiar i d'animals domèstics (2)57 (1)575 - Genètica general. Citogenètica general. Immunogenètica. Evolució. Filogènia (1)579 (1)663/664 - Aliments i nutrició. Enologia. Olis. Greixos (1)... Show moreAreaProducció Animal (19)Indústries Alimentàries (2)Agrosistemes i Medi Ambient (1)ProgramGenètica i Millora Animal (19)Nutrició Animal (2)Qualitat del Producte (2)Benestar Animal (GE) (1)Gestió Integral de Residus Orgànics (1)Tecnologia Alimentària (1)Issue Date2020 (7)2019 (6)2018 (6)Grant agreement numberMINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2013-48742-C2-1-R/ES/FISIOLOGIA GENOMICA DEL DEPOSITO DE GRASA INTRAMUSCULAR EN PORCINO/ (6)MINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2013-48742-C2-2-R/ES/FISIOLOGIA GENOMICA DEL DEPOSITO DE GRASA INTRAMUSCULAR EN PORCINO/ (6)MINECO/Programa Estatal de promoción del talento y su empleabilidad en I+D+I/RYC‑2013‑12573/ES/ / (5)EC/H2020/665919/EU/Opening Sphere UAB-CEI to PostDoctoral Fellows/P-SPHERE (4)MINECO/ /SEV-2015-0533/ES/ / (4)MINECO/Programa Estatal de fomento de la investigación científica y técnica de excelencia/SEV-2015-0533/ES/ / (4)EC/FP7/311794/EU/A whole-systems approach to optimising feed efficiency and reducing the ecological footprint of monogastrics/ECO-FCE (2)MINECO/ PROGRAMA ESTATAL DE INVESTIGACIÓN, DESARROLLO E INNOVACIÓN ORIENTADA A LOS RETOS DE LA SOCIEDAD/AGL2013-48742-C2-1-R/ES/FISIOLOGIA GENOMICA DEL DEPOSITO DE GRASA INTRAMUSCULAR EN PORCINO/ (2)MINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2016-75432-R/ES/DETERMINACION GENETICA DE LA CAPACIDAD INMUNOLOGICA EN PORCINO: IDENTIFICACION DE VARIANTES GENETICAS FUNCIONALES PARA LA IMPLEMENTACION DE SELECCION GENOMICA/ (2)EC/COST/CA15112/EU/Functional Annotation of Animal Genomes-European network/FAANG-Europe (1)... Show moreAvailabilityOpen access (17)Embargoed access (2)Document versionPublished version (16)Accepted version (3)


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