Search
Now showing items 1-10 of 15
Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver
(Frontiers Media, 2023-09-14)
C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
A compendium of genetic regulatory effects across pig tissues
(Nature Research, 2024-01-04)
The Farm Animal Genotype-Tissue Expression (FarmGTEx) project has been established to develop a public resource of genetic regulatory variants in livestock, which is essential for linking genetic ...
PigBiobank: a valuable resource for understanding genetic and biological mechanisms of diverse complex traits in pigs
(Oxford University Press, 2023-11-13)
To fully unlock the potential of pigs as both agricultural species for animal-based protein food and biomedical models for human biology and disease, a comprehensive understanding of molecular and ...
A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs
(Frontiers Media, 2021-11-26)
In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs
(Public Library of Science, 2019-06-27)
The selection in commercial swine breeds for meat-production efficiency has been increasing among the past decades, reducing the intramuscular fat content, which has changed the sensorial and technological ...
Copy Number Variation on ABCC2-DNMBP Loci Affects the Diversity and Composition of the Fecal Microbiota in Pigs
(American Society for Microbiology, 2023-05-31)
Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms ...
Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs
(American Society for Microbiology, 2023-12-14)
The gut microbiota is a key player in the host metabolism. Some bacteria are able to ferment non-digestible compounds and produce short-chain fatty acids that the host can later transform and accumulate ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...