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A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
(Public Library of Science, 2017-05-04)
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some economically important traits in domestic animals. In the present study, ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
Epigenetic regulation of the ELOVL6 gene is associated with a major QTL effect on fatty acid composition in pigs
(BMC, 2015-03-25)
Background: In previous studies on an Iberian x Landrace cross, we have provided evidence that supported the porcine ELOVL6 gene as the major causative gene of the QTL on pig chromosome 8 for palmitic ...
Polymorphism in the ELOVL6 Gene Is Associated with a Major QTL Effect on Fatty Acid Composition in Pigs
(Public Library of Science, 2013-01-14)
Background: The ELOVL fatty acid elongase 6 (ELOVL6), the only elongase related to de novo lipogenesis, catalyzes the ratelimiting step in the elongation cycle by controlling the fatty acid balance in ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...