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Opportunities and limits of combining microbiome and genome data for complex trait prediction
(BMC, 2021-08-06)
Background
Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how ...
Development of a modified plug-flow anaerobic digester for biogas production from animal manures
(MDPI, 2019-07-08)
Traditional plug-flow anaerobic reactors (PFRs) are characterized by lacking a mixing system and operating at high total solid concentrations, which limits their applicability for several kinds of ...
Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method
(Elsevier, 2021-02-19)
Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to ...
CCL21-loaded 3D hydrogels for T cell expansion and differentiation
(Elsevier, 2020-08-13)
Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, ...
A Novel Generation of Tailored Antimicrobial Drugs Based on Recombinant Multidomain Proteins
(MDPI, 2023-03-26)
Antibiotic resistance has exponentially increased during the last years. It is necessary to develop new antimicrobial drugs to prevent and treat infectious diseases caused by multidrug- or extensively-drug ...