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On the holobiont ‘predictome’ of immunocompetence in pigs
(BMC, 2023-05-01)
Background
Gut microbial composition plays an important role in numerous traits, including immune response. Integration of host genomic information with microbiome data is a natural step in the prediction ...
Mutations on a conserved distal enhancer in the porcine C-reactive protein gene impair its expression in liver
(Frontiers Media, 2023-09-14)
C-reactive protein (CRP) is an evolutionary highly conserved protein. Like humans, CRP acts as a major acute phase protein in pigs. While CRP regulatory mechanisms have been extensively studied in humans, ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues
(Oxford University Press, 2023-06-24)
Background
In humans and livestock species, genome-wide association studies (GWAS) have been applied to study the association between variants distributed across the genome and a phenotype of interest. ...
Genome-wide linkage analysis of QTL for growth and body composition employing the PorcineSNP60 BeadChip
(BMC, 2012-05-20)
Background: The traditional strategy to map QTL is to use linkage analysis employing a limited number of markers.
These analyses report wide QTL confidence intervals, making very difficult to identify ...
Copy number variation in the porcine genome inferred from a 60 k SNP BeadChip
(BMC, 2010-10-22)
Background: Recent studies in pigs have detected copy number variants (CNVs) using the Comparative Genomic
Hybridization technique in arrays designed to cover specific porcine chromosomes. The goal of ...
Liver transcriptome profile in pigs with extreme phenotypes of intramuscular fatty acid composition
(BMC, 2012-10-11)
Background: New advances in high-throughput technologies have allowed for the massive analysis of genomic
data, providing new opportunities for the characterization of the transcriptome architectures. ...
Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis
(BMC, 2024-02-12)
Background
Intramuscular fat (IMF) content and its fatty acid (FA) composition are typically controlled by several genes, each with a small effect. In the current study, to pinpoint candidate genes and ...
From SNP co-association to RNA co-expression: Novel insights into gene networks for intramuscular fatty acid composition in porcine
(BMC, 2014-03-26)
Background: Fatty acids (FA) play a critical role in energy homeostasis and metabolic diseases; in the context of livestock species, their profile also impacts on meat quality for healthy human consumption. ...
Differences in Muscle Transcriptome among Pigs Phenotypically Extreme for Fatty Acid Composition
(Public Library of Science, 2014-06-13)
Background: Besides having an impact on human health, the porcine muscle fatty acid profile determines meat quality and taste. The RNA-Seq technologies allowed us to explore the pig muscle transcriptome ...