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Auto-Adhesion Potential of Extraocular Aqp0 during Teleost Development
(Public Library of Science, 2016-05-06)
AQP0 water channels are the most abundant proteins expressed in the mammalian lens fiber membranes where they are essential for lens development and transparency. Unlike other aquaporin paralogs, mammalian ...
The vertebrate Aqp14 water channel is a neuropeptide-regulated polytransporter
(Springer Nature, 2019-12-11)
Water channels (aquaporins) were originally discovered in mammals with fourteen subfamilies now identified (AQP0-13). Here we show that a functional Aqp14 subfamily phylogenetically related to AQP4-type ...
Toward developing recombinant gonadotropin-based hormone therapies for increasing fertility in the flatfish Senegalese sole
(Public Library of Science, 2017-03-22)
Captive flatfishes, such as the Senegalese sole, typically produce very low volumes of sperm. This situation is particularly prevalent in the first generation (F1) of reared sole males, which limits the ...
Mitochondrial aquaporin-8-mediated hydrogen peroxide transport is essential for teleost spermatozoon motility
(Nature Research, 2015-01-14)
Reactive oxygen species (ROS), particularly hydrogen peroxide (H2O2), cause oxidative cell damage and inhibit sperm function. In most oviparous fishes that spawn in seawater (SW), spermatozoa may be ...
The Lineage-Specific Evolution of Aquaporin Gene Clusters Facilitated Tetrapod Terrestrial Adaptation
(Public Library of Science, 2014-11-26)
A major physiological barrier for aquatic organisms adapting to terrestrial life is dessication in the aerial environment. This barrier was nevertheless overcome by the Devonian ancestors of extant ...
The pH sensitivity of Aqp0 channels in tetraploid and diploid teleosts
(Wiley Open Access, 2015-02-09)
Water homeostasis and the structural integrity of the vertebrate lens is partially mediated by AQP0
channels. Emerging evidence indicates that external pH may be involved in channel gating. Here we ...