Antimicrobial removal on piglets promotes health and higher bacterial diversity in the nasal microbiota
Gonçalves dos Santos, José Maurício
The view on antimicrobials has dramatically changed due to the increased knowledge on the importance of microbiota composition in different body parts. Antimicrobials can no longer be considered only beneficial, but also potentially deleterious for favourable bacterial populations. Still, the use of metaphylactic antimicrobial treatment at early stages of life is a practice in use in porcine production. Many reports have shown that antibiotics can critically affect the gut microbiota, however the effect of perinatal antimicrobial treatment on the nasal microbiota has not been explored yet. To gain insights on the potential changes in nasal microbial composition due to antimicrobial treatments, piglets from two different farms were sampled at weaning. The nasal microbiota was analysed when antimicrobial treatment was used early in life, and later, when no antimicrobial treatment was used during the lactation period. Removal of perinatal antimicrobials resulted in an increased bacterial diversity in nasal microbiota at weaning. Concurrently, elimination of antimicrobials produced an increase in the relative abundance of Prevotella and Lactobacillus, and a decrease in Moraxella and Bergeyella. These changes in microbiota composition were accompanied by an improvement of the piglets’ health and a higher productivity in the nursery phase.
619 - Veterinària
Is part of
Correa-Fiz, Florencia, José Maurício Gonçalves dos Santos, Francesc Illas, and Virginia Aragon. 2019. "Antimicrobial Removal On Piglets Promotes Health And Higher Bacterial Diversity In The Nasal Microbiota". Scientific Reports 9 (1). Springer Nature. doi:10.1038/s41598-019-43022-y.
Grant agreement number
MINECO/Programa estatal de I+D+I orientada a los retos de la sociedad/AGL2016-77361-R/ES/Papel de la microbiota respiratoria en la prevención de las enfermedades causadas por los colonizadores precoces del tracto respiratorio superior del cerdo/
This item appears in the following Collection(s)
The following license files are associated with this item: