Now showing items 1-3 of 3

    • Bacterial inclusion bodies are industrially exploitable amyloids 

      de Marco, Ario; Ferrer-Miralles, Neus; Garcia-Fruitós, Elena; Mitraki, Anna; Peternel, Spela; Rinas, Ursula; Trujillo-Roldán, Mauricio A; Valdez-Cruz, Norma A; Vázquez, Esther; Villaverde, Antonio (FEMS Microbiology Reviews, 2018-10-24) Producció de Remugants
      Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein ...
    • Exploring the use of leucine zippers for the generation of a new class of inclusion bodies for pharma and biotechnological applications 

      Roca-Pinilla, Ramon; Fortuna, Sara; Natalello, Antonino; Sánchez-Chardi, Alejandro; Ami, Diletta; Arís, Anna; Garcia-Fruitós, Elena (Microbial Cell Factories, 2020-09-04) Producció de Remugants
      Background Inclusion bodies (IBs) are biologically active protein aggregates forming natural nanoparticles with a high stability and a slow-release behavior. Because of their nature, IBs have been ...
    • High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage 

      Berdún, Rebeca; Obis, Èlia; Mota-Martorell, Natàlia; Bassols, Anna; Valent, Daniel; Serrano, José C. E.; Martín-Garí, Meritxell; Rodríguez-Palmero, María; Moreno-Muñoz, José Antonio; Tibau , Joan ; Quintanilla, Raquel; Pamplona, Reinald; Portero-Otín, Manuel; Jové, Mariona (Antioxidants, 2024-01-26) Genètica i Millora Animal
      Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by ...