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LC-MS/MS Detection of Karlotoxins Reveals New Variants in Strains of the Marine Dinoflagellate Karlodinium veneficum from the Ebro Delta (NW Mediterranean)
(MDPI, 2017-12-18)
A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the detection and quantitation of karlotoxins in the selected reaction monitoring (SRM) mode. This novel method was ...
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
(BMC, 2022-12-13)
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective ...
A pilot RNA-seq study in 40 pietrain ejaculates to characterize the porcine sperm microbiome
(Elsevier, 2020-08-15)
The microbiome plays a key role in homeostasis and health and it has been also linked to fertility and semen quality in several animal species including swine. Despite the more than likely importance ...
Insect glycerol transporters evolved by functional co-option and gene replacement
(Nature Research, 2015-07-17)
Transmembrane glycerol transport is typically facilitated by aquaglyceroporins in Prokaryota and Eukaryota. In holometabolan insects however, aquaglyceroporins are absent, yet several species possess ...
Living on the Edge: Demography of the Slender-Billed Gull in the Western Mediterranean
(Public Library of Science, 2014-03-24)
Small and peripheral populations are typically vulnerable to local extinction processes but important for the metapopulation dynamics of species. The Slender-billed gull (Chroicocephalus genei) is a ...
Gestational Caloric Restriction Alters Adipose Tissue Methylome and Offspring’s Metabolic Profile in a Swine Model
(MDPI, 2024-01-17)
Limited nutrient supply to the fetus results in physiologic and metabolic adaptations that have unfavorable consequences in the offspring. In a swine animal model, we aimed to study the effects of ...
Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery
(BMC, 2023-07-03)
Background Most interactions between the host and its microbiota occur at the gut barrier, and primary colonizers
are essential in the gut barrier maturation in the early life. The mother–ofspring ...
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
(MDPI, 2024-01-26)
Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by ...
Safety and Efficacy upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued Virus
(MDPI, 2024-01-05)
The introduction of three single nucleotide mutations into the genome of the virulent RVFV
ZH548 strain allows for the rescue of a fully attenuated virus in mice (ZH548-rA2). These mutations
are located ...