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kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs
(BMC, 2019-03-13)
Background: To date, the molecular mechanisms that underlie residual feed intake (RFI) in pigs are unknown. Results
from diferent genome‑wide association studies and gene expression analyses are not ...
Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits
(Elsevier, 2023-02-24)
In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is ...
A gene co-association network regulating gut microbial communities in a Duroc pig population
(BMC, 2021-02-21)
Background. Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic ...
Integrating genome-wide co-association and gene expression to identify putative regulators and predictors of feed efficiency in pigs
(BMC, 2019-09-02)
Background: Feed efciency (FE) has a major impact on the economic sustainability of pig production. We used a
systems‑based approach that integrates single nucleotide polymorphism (SNP) co‑association ...
Diversity across major and candidate genes in European local pig breeds
(Public Library of Science, 2018-11-20)
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...
A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs
(Frontiers Media, 2021-11-26)
In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. ...
About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
(BMC, 2019-06-24)
Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to
understand how gene expression is genetically regulated in a context-dependent manner. In ...
Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits
(Nature Research, 2017-01-05)
Meat quality traits have an increasing importance in the pig industry because of their strong impact on
consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to ...
Genetic architecture of innate and adaptive immune cells in pigs
(Frontiers Media, 2023-02-06)
Pig industry is facing new challenges that make necessary to reorient breeding programs to produce more robust and resilient pig populations. The aim of the present work was to study the genetic determinism ...