Fast analysis of relevant contaminants mixture in commercial shellfish
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Lopez de Alda, M.
One of the major challenges currently faced is to develop systematic ways of addressing chemical mixtures in environmental assessment. With this purpose, a simple, rapid, and sensitive method for the detection and quantification of a mixture of relevant contaminants in molluscs has been developed. The method is based on QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) and Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry (UHPLC-HRMS). It includes a mixture of 23 compounds formed by pesticides, endocrine disruptors and pharmaceuticals (metolachlor, simazine, desethylatrazine, atrazine, thiabendazole, diazinon, malathion, bentazone, MCPA, propanil, acetamiprid, imidacloprid, caffeine, bisphenol A, triclosan, triclocarban, methylparaben, ethylparaben, propylparaben, 1H-benzotriazole, sulfamethoxazole, venlafaxine and carbamazepine). The method was developed and validated in 4 different types of shellfish of high commercial interest such as mussel (Mytilus galloprovincialis), oyster (Crassostrea gigas), cockle (Cerastoderma edule) and razor shell (Solen marginatus). The mean percentage of recoveries obtained for all the compounds in each mollusc type (intra-specie) ranged from 96% to 107% showing the good performance of the method developed. The relative standard deviation was under 10% for the intra-day and 17% inter-day analyses. Method detection limits and method quantification limits were below 10 ng/g dry weight for all the species and compounds targeted. Finally, the method was applied to aquaculture samples, oysters and cockles, from Ebro Delta (Spain), after some episodes of mortality occurred in 2017. A high level of bisphenol A was detected in C. edule which may explain the mortality suffered by this organism. C. gigas presented low levels of metolachlor, bentazone, acetamiprid, and methylparaben.
574 - Ecologia general i biodiversitat
639 - Caça. Pesca. Piscicultura
Is part of
Álvarez-Muñoz, D., M. Rambla-Alegre, N. Carrasco, M. Lopez de Alda, and D. Barceló. 2019. "Fast Analysis Of Relevant Contaminants Mixture In Commercial Shellfish". Talanta 205: 119884. Elsevier BV. doi:10.1016/j.talanta.2019.04.085.
Grant agreement number
MINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/CTM2015-73179-JIN/ES/IDENTIFICACION DE XENOBIOTICOS BIOACUMULABLES EN MEJILLON SIGUIENDO UN ENFOQUE METABOLOMICO: EXPOSICION HUMANA Y AMBIENTAL/XENOMETABOLIC
MINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/RTA2015-00004- 00-00/ES/Gestión sanitaria integrada de las enfermedades emergentes de bivalvos con interés comercial en el Mediterráneo espanyol/EMERGER
EC/FP7/603437/EU/Solutions for present and future emerging pollutants in land and water resources management/SOLUTIONS
Agrosistemes i Medi Ambient
Aigües Marines i Continentals
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