Haptoglobin serum concentration is a suitable biomarker to assess the efficacy of a feed additive in pigs
Visualitza/Obre
Data de publicació
2010-04-01ISSN
1751-7311
Resum
Levels of haptoglobin and Pig-major acute phase protein (MAP) were analysed in animals from a commercial herd receiving or
not a diet enriched with an additive. The group receiving the additive exhibited a decrease in haptoglobin after 3 weeks,
suggesting that a better health status has been established, together with an improvement in total body weight and average
daily gain. In contrast, Pig-MAP does not significantly change under these conditions. Aujeszky live modified vaccination, which
is compulsory in Spain, did cause a significant increment in haptoglobin serum concentration although it did not affect Pig-MAP.
The response of acute phase proteins to vaccination was similar in both control and additive-treated groups. Interleukins (IL)-1b
and IL-6 was below the detection limits in most of the animals. In conclusion, this study shows that haptoglobin serum
concentration, but not Pig-MAP, is a good biomarker to monitorize production parameters and for monitoring Aujeszky modified
live vaccine in pigs reared under standard commercial conditions.
Tipus de document
Article
Versió del document
Versió publicada
Llengua
English
Matèries (CDU)
619 - Veterinària
Pàgines
7
Publicat per
Elsevier
Publicat a
Animal
Citació
Saco, Y., L. Fraile, M. Giménez, R. Pato, M. Montoya, and A. Bassols. 2010. “Haptoglobin Serum Concentration Is a Suitable Biomarker to Assess the Efficacy of a Feed Additive in Pigs.” Animal 4 (9): 1561–1567. doi: 10.1017/s1751731109991418
Número de l'acord de la subvenció
MEC/ /AGL2006-13809-C03-01/ES/Nuevas estrategias vacunales e inmunomoduladores basadas en la estimulación de las células dendríticas porcinas empleando como modelo el virus de la gripe/GAN
MEC/ /AGL2006-02364/ES/Identificación de marcadores biologicos de estres en el ganado vacuno y porcino: una aproximación proteómica/GAN
Programa
Sanitat Animal
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