Haptoglobin serum concentration is a suitable biomarker to assess the efficacy of a feed additive in pigs
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Publication date
2010-04-01ISSN
1751-7311
Abstract
Levels of haptoglobin and Pig-major acute phase protein (MAP) were analysed in animals from a commercial herd receiving or
not a diet enriched with an additive. The group receiving the additive exhibited a decrease in haptoglobin after 3 weeks,
suggesting that a better health status has been established, together with an improvement in total body weight and average
daily gain. In contrast, Pig-MAP does not significantly change under these conditions. Aujeszky live modified vaccination, which
is compulsory in Spain, did cause a significant increment in haptoglobin serum concentration although it did not affect Pig-MAP.
The response of acute phase proteins to vaccination was similar in both control and additive-treated groups. Interleukins (IL)-1b
and IL-6 was below the detection limits in most of the animals. In conclusion, this study shows that haptoglobin serum
concentration, but not Pig-MAP, is a good biomarker to monitorize production parameters and for monitoring Aujeszky modified
live vaccine in pigs reared under standard commercial conditions.
Document Type
Article
Document version
Published version
Language
English
Subject (CDU)
619 - Veterinary science
Pages
7
Publisher
Elsevier
Is part of
Animal
Citation
Saco, Y., L. Fraile, M. Giménez, R. Pato, M. Montoya, and A. Bassols. 2010. “Haptoglobin Serum Concentration Is a Suitable Biomarker to Assess the Efficacy of a Feed Additive in Pigs.” Animal 4 (9): 1561–1567. doi: 10.1017/s1751731109991418
Grant agreement number
MEC/ /AGL2006-13809-C03-01/ES/Nuevas estrategias vacunales e inmunomoduladores basadas en la estimulación de las células dendríticas porcinas empleando como modelo el virus de la gripe/GAN
MEC/ /AGL2006-02364/ES/Identificación de marcadores biologicos de estres en el ganado vacuno y porcino: una aproximación proteómica/GAN
Program
Sanitat Animal
This item appears in the following Collection(s)
- ARTICLES CIENTÍFICS [2680]
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0/