Networks of inbreeding coefficients in a selected population of rabbits
Ver/Abrir
Autor/a
Rodríguez‐Ramilo, Silvia T.
Reverter, Antonio
Sánchez, Juan P.
Fernández, Jesus
Velasco‐Galilea, Maria
González, Olga
Fecha de publicación
2020-08-17ISSN
0931-2668
Resumen
The correlation between pedigree and genomic‐based inbreeding coefficients is usually discussed in the literature. However, some of these correlations could be spurious. Using partial correlations and information theory, it is possible to distinguish a significant association between two variables which is independent from associations with a third variable. The objective of this study is to implement partial correlations and information theory to assess the relationship between different inbreeding coefficients using a selected population of rabbits. Data from pedigree and genomic information from a 200K SNP chip were available. After applying filtering criteria, the data set comprised 437 animals genotyped for 114,604 autosomal SNP. Fifteen pedigree‐ and genome‐based inbreeding coefficients were estimated and used to build a network. Recent inbreeding coefficient based on runs of homozygosity had 9 edges linking it with different inbreeding coefficients. Partial correlations and information theory approach allowed to infer meaningful associations between inbreeding coefficients and highlighted the importance of the recent inbreeding based on runs of homozygosity, but a good proxy of it could be those pedigree‐based definitions reflecting recent inbreeding.
Tipo de documento
Artículo
Versión del documento
Versión aceptada
Lengua
Inglés
Materias (CDU)
575 - Genética general. Citogenética general. Inmunogenética. Evolución. Filogenia
59 - Zoología
619 - Veterinaria
636 - Explotación y cría de animales. Cría del ganado y de animales domésticos
Páginas
31
Publicado por
Wiley
Publicado en
Journal of Animal Breeding and Genetics
Citación
Rodríguez‐Ramilo, Silvia T., Antonio Reverter, Juan P. Sánchez, Jesus Fernández, Maria Velasco‐Galilea, Olga González, and Miriam Piles. 2020. "Networks Of Inbreeding Coefficients In A Selected Population Of Rabbits". Journal Of Animal Breeding And Genetics 137 (6): 599-608. doi:10.1111/jbg.12500.
Número del acuerdo de la subvención
EC/H2020/633531/EU/Adapting the feed, the animal and the feeding techniques to improve the efficiency and sustainability of monogastric livestock production systems/Feed-a-Gene
INIA/Programa Estatal de I+D+I orientada a los retos de la sociedad/RTA2014-00015-C02-01/ES/Mejora de la eficiencia alimentaria en cerdos y conejos. Determinismo genético y estrategias de selección/
Program
Genètica i Millora Animal
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