dc.contributor.author | Temple, Déborah | |
dc.contributor.author | Jiménez, Marta | |
dc.contributor.author | Escribano, Damián | |
dc.contributor.author | Martín-Valls, Gerard | |
dc.contributor.author | Díaz, Ivan | |
dc.contributor.author | Manteca, Xavier | |
dc.contributor.other | Producció Animal | ca |
dc.date.accessioned | 2020-12-04T12:18:44Z | |
dc.date.available | 2020-12-04T12:18:44Z | |
dc.date.issued | 2020-10-16 | |
dc.identifier.citation | Temple D, Jiménez M, Escribano D, Martín-Valls G, Díaz I, Manteca X. Welfare Benefits of Intradermal Vaccination of Piglets. Animals (Basel). 2020 Oct 16;10(10):1898. doi: 10.3390/ani10101898. PMID: 33081216; PMCID: PMC7602853. | ca |
dc.identifier.issn | 2076-2615 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12327/1003 | |
dc.description.abstract | Vaccination is reported as a stressful and painful event for animals. This study investigated whether needle-free intradermal vaccination improves the welfare of weaned pigs through the reduction of stress and pain biomarkers and improvement of behavioural parameters compared to traditional intramuscular injection with a needle. A total of 339 weaned piglets were allocated to 3 treatment groups: Intradermal Application of Liquids (IDAL) pigs, vaccinated against Porcine Circovirus type 2 (PCV2) by means of intradermal vaccination using a needle-free device Porcilis® PCV ID; Intramuscular (IM) pigs vaccinated against PCV2 with Porcilis® PCV intramuscularly with a needle; CONTROL pigs were managed identically but did not receive any vaccine injection. At the time of the injection, the reaction of IDAL piglets was similar to control piglets, whereas a greater percentage of piglets vaccinated intramuscularly displayed high-pitch vocalizations (7% CONTROL, 7% IDAL, 32% IM) and retreat attempts (3% CONTROL, 7% IDAL, 39% IM). The day after vaccination, IDAL piglets did not differ from the control piglets for any of the behavioural variables studied through scan samplings. IM piglets showed a lower frequency of social negative interactions (p = 0.001) and rope manipulation (p = 0.04) compared to the CONTROL group. Resting postures did not differ between treatments. At 28 h post-vaccination, IDAL piglets presented lower blood C-reactive protein levels (CONTROL = 20 μg/mL; IDAL = 39 μg/mL; IM = 83 μg/mL, p < 0.0001) and blood Haptoglobin (CONTROL = 1.8 mg/mL; IDAL = 1.9 mg/mL vs. IM = 3.1 mg/mL, p < 0.0001) compared to IM piglets. Salivary chromogranin A and alpha-amylase did not differ between treatment groups when measured 25 min post-vaccination. The method of vaccination did not affect the growth of the piglets or their rectal temperature. These results support that needle-free intradermal vaccination reduces vaccination-related pain in growing pigs. | ca |
dc.format.extent | 12 | ca |
dc.language.iso | eng | ca |
dc.publisher | MDPI | ca |
dc.relation.ispartof | Animals | ca |
dc.rights | Attribution 4.0 International | ca |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.title | Welfare Benefits of Intradermal Vaccination of Piglets | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.subject.udc | 619 | ca |
dc.identifier.doi | https://doi.org/10.3390/ani10101898 | ca |
dc.contributor.group | Sanitat Animal | ca |