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Removal of the Erns RNase Activity and of the 39 Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease
(American Society for Microbiology, 2022-06-27)
In this study, we assessed the potential synergistic effect of the Erns RNase activity and the poly-U insertion in the 3′ untranslated region (UTR) of the low-virulence classical swine fever virus (CSFV) ...
Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae
(MDPI, 2024-05-23)
In this study, we pioneered an alternative technology for manufacturing subunit influenza
hemagglutinin (HA)-based vaccines. This innovative method involves harnessing the pupae of the
Lepidoptera ...
Zika vector competence data reveals risks of outbreaks: the contribution of the European ZIKAlliance project
(Nature Research, 2022-08-02)
First identified in 1947, Zika virus took roughly 70 years to cause a pandemic unusually associated with virus-induced brain damage in newborns. Zika virus is transmitted by mosquitoes, mainly Aedes ...
Biogas Upgrading and Ammonia Recovery from Livestock Manure Digestates in a Combined Electromethanogenic Biocathode—Hydrophobic Membrane System
(MDPI, 2021-01-19)
Anaerobic digestion process can be improved in combination with bioelectrochemical systems in order to recover energy and resources from digestates. An electromethanogenic microbial electrolysis cell ...
A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
(BMC, 2020-01-14)
Background: Virus neutralization test (VNT) is widely used for serological survey of classical swine fever (CSF) and efficacy evaluation of CSF vaccines. However, VNT is a time consuming procedure that ...
Chicken liver is a potential reservoir of bacteriophages and phage-derived particles containing antibiotic resistance genes
(Wiley Open Access, 2022-04-29)
Poultry meat production is one of the most important agri-food industries in the world. The selective pressure exerted by widespread prophylactic or therapeutic use of antibiotics in intensive chicken ...
Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity
(Frontiers Media, 2020-10-23)
Identification of African Swine Fever Virus Transcription within Peripheral Blood Mononuclear Cells of Acutely Infected Pigs
(MDPI, 2021-11-22)
African swine fever virus (ASFV) has become widespread in Europe, Asia and elsewhere, thereby causing extensive economic losses. The viral genome includes nearly 200 genes, but their expression within ...
Spatiotemporal monitoring of selected pathogens in Iberian ibex (Capra pyrenaica)
(Wiley, 2020-04-17)
An epidemiological surveillance programme was carried out to assess exposure and spatiotemporal patterns of selected pathogens (Brucella spp., Mycobacterium avium subsp. paratuberculosis (MAP), Mycoplasma ...
Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
(Elsevier, 2021-09-21)
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the ...