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Genetic diversity and selection signatures of the beef ‘Charolais de Cuba’ breed
(Scientific Reports, 2018-07-20)
In this study, we used BovineSNP50 Genotyping BeadChip data to estimate the structure, putative
ancestral origin as well as to identify regions with selective sweeps that may have had an important
role ...
Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(Journal of Animal Science and Biotechnology, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
A functional regulatory variant of MYH3 influences muscle fiber-type composition and intramuscular fat content in pigs
(PLoS Genetics, 2019-10-11)
Muscle development and lipid accumulation in muscle critically affect meat quality of livestock. However, the genetic factors underlying myofiber-type specification and intramuscular fat (IMF) accumulation ...
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
(Scientific Reports, 2018-08-28)
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its physiological similarities. The aim of this study was to describe the ...
Modulatory effect of protein and carotene dietary levels on pig gut microbiota
(Scientific Reports, 2019-10-10)
In this study we investigated the impact of dietary protein and carotene levels on microbial functions and composition during the last month of purebred fattening Duroc pigs. Fecal microbiota was ...
Integration of GWAS, pathway and network analyses reveals novel mechanistic insights into the synthesis of milk proteins in dairy cows
(Scientific Reports, 2018-01-12)
The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, ...
Integrating genome-wide co-association and gene expression to identify putative regulators and predictors of feed efficiency in pigs
(Genetics Selection Evolution, 2019-09-02)
Background: Feed efciency (FE) has a major impact on the economic sustainability of pig production. We used a
systems‑based approach that integrates single nucleotide polymorphism (SNP) co‑association ...
Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese-making properties and milk composition in Montbéliarde cows
(Genetics Selection Evolution, 2019-07-01)
Background
Milk quality in dairy cattle is routinely assessed via analysis of mid-infrared (MIR) spectra; this approach can also be used to predict the milk’s cheese-making properties (CMP) and ...
About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
(BMC Genomics, 2019-06-24)
Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to
understand how gene expression is genetically regulated in a context-dependent manner. In ...
Link-HD: a versatile framework to explore and integrate heterogeneous microbial communities
(Bioinformatics, 2019-11-18)
Motivation We present Link-HD, an approach to integrate multiple datasets. Link-HD is a generalization of ‘Structuration des Tableaux A Trois Indices de la Statistique–Analyse Conjointe de Tableaux’, a ...