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Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity
(Nature Research, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
Genetic parameters and associated genomic regions for global immunocompetence and other health-related traits in pigs
(Nature Research, 2020-10-28)
The inclusion of health-related traits, or functionally associated genetic markers, in pig breeding programs could contribute to produce more robust and disease resistant animals. The aim of the present ...
Gut eukaryotic communities in pigs: diversity, composition and host genetics contribution
(BMC, 2020-05-07)
Background
The pig gut microbiome harbors thousands of species of archaea, bacteria, viruses and eukaryotes such as protists and fungi. However, since the majority of published studies have been focused ...
Machine learning applied to transcriptomic data to identify genes associated with feed efficiency in pigs
(BMC, 2019-03-13)
Background: To date, the molecular mechanisms that underlie residual feed intake (RFI) in pigs are unknown. Results
from diferent genome‑wide association studies and gene expression analyses are not ...
Integrating genome-wide co-association and gene expression to identify putative regulators and predictors of feed efficiency in pigs
(BMC, 2019-09-02)
Background: Feed efciency (FE) has a major impact on the economic sustainability of pig production. We used a
systems‑based approach that integrates single nucleotide polymorphism (SNP) co‑association ...
A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs
(Frontiers Media, 2021-11-26)
In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identifcation of regulatory regions
(Nature Research, 2018-02-01)
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes
associated with meat quality traits in pigs. We performed a genome-wide association study with ...
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds
(Nature Research, 2020-06-17)
Intramuscular fat content and its fatty acid composition affect porcine meat quality and its nutritional value. The present work aimed to identify genomic variants regulating the expression in the porcine ...
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
(Nature Research, 2020-08-18)
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained in adipose tissue and muscle. The present study aimed to find genomic ...