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Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply
(BMC, 2020-01-17)
Background
The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed ...
Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity
(Nature Research, 2020-03-25)
Global prevalence of obesity has increased to epidemic proportions over the past 40 years, with childhood obesity reaching alarming rates. In this study, we determined changes in liver and adipose tissue ...
Genetic parameters and associated genomic regions for global immunocompetence and other health-related traits in pigs
(Nature Research, 2020-10-28)
The inclusion of health-related traits, or functionally associated genetic markers, in pig breeding programs could contribute to produce more robust and disease resistant animals. The aim of the present ...
Role of AMPK signalling pathway during compensatory growth in pigs
(BioMed Central, 2018-09-17)
Background: The molecular basis of compensatory growth in monogastric animals has not yet been fully explored.
Herewith, in this study we aim to determine changes in the pig skeletal muscle transcriptome ...
Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle
(BMC, 2017-08-10)
Background: The genetic basis of muscle fat deposition in pigs is not well known. So far, we have only identified a limited number of genes involved in the absorption, transport, storage and catabolism ...
Molecular phenomics of a high-calorie diet-induced porcine model of prepubertal obesity
(Elsevier, 2020-04-24)
As obesity incidence is alarmingly rising among young individuals, we aimed to characterize an experimental model of this situation, considering the similarity between human and porcine physiology. For ...
Diversity across major and candidate genes in European local pig breeds
(Public Library of Science, 2018-11-20)
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...