Browsing by Subject "577"
Now showing items 1-8 of 8
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A Novel Generation of Tailored Antimicrobial Drugs Based on Recombinant Multidomain Proteins
(Pharmaceutics, 2023-03-26)Antibiotic resistance has exponentially increased during the last years. It is necessary to develop new antimicrobial drugs to prevent and treat infectious diseases caused by multidrug- or extensively-drug ... -
Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method
(Journal of Supercritical Fluids, 2021-02-19)Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to ... -
CCL21-loaded 3D hydrogels for T cell expansion and differentiation
(Biomaterials, 2020-08-13)Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, ... -
Development of a modified plug-flow anaerobic digester for biogas production from animal manures
(Energies, 2019-07-08)Traditional plug-flow anaerobic reactors (PFRs) are characterized by lacking a mixing system and operating at high total solid concentrations, which limits their applicability for several kinds of ... -
Genome‐wide detection of copy number variants in European autochthonous and commercial pig breeds by whole‐genome sequencing of DNA pools identified breed‐characterising copy number states
(Animal Genetics, 2020-06-08)In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic ... -
Near infrared spectroscopy for fast characterization of animal by products feedstocks for biogas production: Calibration of a handheld device
(Biomass and Bioenergy, 2022-12-28)Anaerobic digestion performance is highly influenced by the chemical composition and flow of substrates. This work evaluates the feasibility of a handheld near infrared spectrometer to predict moisture, ... -
Opportunities and limits of combining microbiome and genome data for complex trait prediction
(Genetics Selection Evolution, 2021-08-06)Background Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how ... -
Startup strategy for nitrogen removal via nitrite in a BAF system
(Bioprocess and Biosystems Engineering, 2018-10-26)A biological aerated filter (BAF) pilot plant consisting of two reactors (aerobic and anoxic one) was used to determine a strategy to remove nitrogen via nitrite. RNA/DNA analysis was performed to assess ...