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Systems analysis reveals complex biological processes during virus infection fate decisions
(Cold Spring Harbor Laboratory Press, 2019-05-28)
The processes and mechanisms of virus infection fate decisions that are the result of a dynamic virus-immune system interaction with either an efficient effector response and virus elimination or an ...
Cross-protection against African swine fever virus upon intranasal vaccination is associated with an adaptive-innate immune crosstalk
(Public Library of Science, 2022-11-09)
African swine fever virus (ASFV) is causing a worldwide pandemic affecting the porcine industry and leading to important global economic consequences. The virus causes a highly lethal hemorrhagic disease ...
Evaluation of P22 antigenic complex for the immuno-diagnosis of Tuberculosis in BCG vaccinated and unvaccinated goats
(Frontiers Media, 2020-07-03)
Current eradication strategies of tuberculosis (TB) in goats mainly rely on the single intradermal tuberculin test (SIT) and single intradermal cervical comparative tuberculin tests (SICCTs). TB vaccination ...
Protective effect of a polyvalent influenza DNA vaccine in pigs
(Elsevier, 2017-11-23)
Background: Influenza A virus in swine herds represents a major problem for the swine industry and poses a
constant threat for the emergence of novel pandemic viruses and the development of more effective ...
Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis
(Public Library of Science, 2018-01-31)
Very solid evidence suggests that the core of full length PrPSc is a 4-rung β-solenoid, and that individual PrPSc subunits stack to form amyloid fibers. We recently used limited proteolysis to map the ...
Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain
(National Academy of Sciences, 2020-09-18)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of COVID-19, is considered a zoonotic pathogen mainly transmitted human to human. Few reports indicate that pets may ...
Neoplastic lesions in domestic pigs detected at slaughter: literature review and a 20-year review (1998–2018) of carcass inspection in Catalonia
(BMC, 2021-04-07)
Background: The present paper reviews the occurrence of neoplasms in swine and presents a case series of 56 tumors submitted to the Slaughterhouse Support Network (Servei de Suport a Escorxadors [SESC] ...
Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model
(MDPI, 2021-03-08)
Neurotrophins constitute a group of growth factor that exerts important functions in the nervous system of vertebrates. They act through two classes of transmembrane receptors: tyrosine-kinase receptors ...
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
(BMC, 2022-12-13)
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its occurrence is unlikely to be controlled through selective ...
Cutaneous apocrine cystomatosis in three slaughter-aged pigs
(SAGE Publications, 2019-12-09)
Apocrine cystomatosis is a rare condition characterized by clusters of cystically dilated sweat glands or other specialized apocrine glands. Cystic dilation of cutaneous sweat glands has been described ...