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Protective Immunity to Listeria Monocytogenes Infection Mediated by Recombinant Listeria innocua Harboring the VGC Locus
(Public Library of Science, 2012-04-19)
In this study we propose a novel bacterial vaccine strategy where non-pathogenic bacteria are complemented with traits
desirable for the induction of protective immunity. To illustrate the proof of ...
A Protein Misfolding Shaking Amplificationbased method for the spontaneous generation of hundreds of bona fide prions
(Nature Research, 2024-03-08)
Prion diseases are a group of rapidly progressing neurodegenerative disorders
caused by the misfolding of the endogenous prion protein (PrPC) into a
pathogenic form (PrPSc). This process, despite being ...
Immunisation efficacy of a stabilised SARS-CoV-2 spike glycoprotein in two geriatric animal models
(Nature Research, 2024-02-27)
AgeisassociatedwithreducedefficacyofvaccinesandlinkedtohigherriskofsevereCOVID-19.Herewe
determined the impact of ageing on the efficacy of a SARS-CoV-2 vaccine based on a stabilised Spike
glycoprotein ...
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection
(Nature Research, 2024-03-21)
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) vaccines are crucial to fight against the coronavirus disease 2019
pandemic. Most vaccines are based on a mutated version ...
Field evaluation of an automated mosquito surveillance system which classifies Aedes and Culex mosquitoes by genus and sex
(BMC, 2024-03-01)
Background Mosquito‑borne diseases are a major concern for public and veterinary health authorities, highlighting
the importance of efective vector surveillance and control programs. Traditional ...
Protection of Spanish Ibex (Capra pyrenaica) against Bluetongue Virus Serotypes 1 and 8 in a Subclinical Experimental Infection
(Public Library of Science, 2012-05-30)
Many wild ruminants such as Spanish ibex (Capra pyrenaica) are susceptible to Bluetongue virus (BTV) infection, which
causes disease mainly in domestic sheep and cattle. Outbreaks involving either BTV ...
Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection
(BMC, 2012-04-19)
The present study characterized the homologous and heterologous immune response in type-I porcine
reproductive and respiratory syndrome virus (PRRSV) infection. Two experiments were conducted: in ...
Conserved Synthetic Peptides from the Hemagglutinin of Influenza Viruses Induce Broad Humoral and T-Cell Responses in a Pig Model
(Public Library of Science, 2012-07-16)
Outbreaks involving either H5N1 or H1N1 influenza viruses (IV) have recently become an increasing threat to cause potential
pandemics. Pigs have an important role in this aspect. As reflected in the ...
Development of a new loop-mediated isothermal amplification test for the sensitive, rapid, and economic detection of different genotypes of Classical swine fever virus
(Frontiers Media, 2024-04-15)
Background: Classical swine fever virus (CSFV) remains one of the most
important pathogens in animal health. Pathogen detection relies on viral RNA
extraction followed by RT-qPCR. Novel technologies ...
VtaA8 and VtaA9 from Haemophilus parasuis delay phagocytosis by alveolar macrophages
(BMC, 2012-07-27)
Haemophilus parasuis, a member of the family Pasteurellaceae, is a common inhabitant of the upper respiratory tract
of healthy pigs and the etiological agent of Glässer’s disease. As other virulent ...