Browsing PUBLICACIONS CIENTÍFIQUES by Subject "577"
Now showing items 1-11 of 11
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A Novel Generation of Tailored Antimicrobial Drugs Based on Recombinant Multidomain Proteins
(Pharmaceutics, 2023-03-26)Antibiotic resistance has exponentially increased during the last years. It is necessary to develop new antimicrobial drugs to prevent and treat infectious diseases caused by multidrug- or extensively-drug ... -
Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method
(Journal of Supercritical Fluids, 2021-02-19)Fabry disease is a lysosomal storage disease arising from a deficiency of the enzyme α-galactosidase A (GLA). The enzyme deficiency results in an accumulation of glycolipids, which over time, leads to ... -
CCL21-loaded 3D hydrogels for T cell expansion and differentiation
(Biomaterials, 2020-08-13)Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, ... -
Development of a modified plug-flow anaerobic digester for biogas production from animal manures
(Energies, 2019-07-08)Traditional plug-flow anaerobic reactors (PFRs) are characterized by lacking a mixing system and operating at high total solid concentrations, which limits their applicability for several kinds of ... -
Evaluating Host Defense Peptides: A Comparative Analysis of Synthetic Peptides and Recombinant Concatemers
(Biomolecules, 2025-07-08)The global antibiotic resistance crisis raises concerns about antibiotic use, and alternative strategies are urgently needed. In this context, host defense peptides (HDPs) have rapidly gained interest. ... -
Genome‐wide detection of copy number variants in European autochthonous and commercial pig breeds by whole‐genome sequencing of DNA pools identified breed‐characterising copy number states
(Animal Genetics, 2020-06-08)In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic ... -
Investigation of the role of the L‑DOPA pathway in the production of melanin in Monilinia spp. and its relationship with fungal development
(European Journal of Plant Pathology, 2026-03-26)Monilinia spp., the causal agent of brown rot in stone fruits, relies on melanin biosynthesis for development, survival, and longevity. In this study, we identified for the first time the presence of ... -
Near infrared spectroscopy for fast characterization of animal by products feedstocks for biogas production: Calibration of a handheld device
(Biomass and Bioenergy, 2022-12-28)Anaerobic digestion performance is highly influenced by the chemical composition and flow of substrates. This work evaluates the feasibility of a handheld near infrared spectrometer to predict moisture, ... -
Opportunities and limits of combining microbiome and genome data for complex trait prediction
(Genetics Selection Evolution, 2021-08-06)Background Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how ... -
Startup strategy for nitrogen removal via nitrite in a BAF system
(Bioprocess and Biosystems Engineering, 2018-10-26)A biological aerated filter (BAF) pilot plant consisting of two reactors (aerobic and anoxic one) was used to determine a strategy to remove nitrogen via nitrite. RNA/DNA analysis was performed to assess ... -
Using transcriptomic data to improve the prediction of immunity traits in pigs
(Animal, 2025-12-16)Considering health-related traits among breeding selection criteria has been proposed as a way to improve pig robustness. This study investigated the potential of whole blood RNA-sequencing data for ...