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β-Cyclodextrins as affordable antivirals to treat coronavirus infection
(Elsevier, 2023-06-08)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. ...
Antimicrobial Susceptibility Testing of Porcine Bacterial Pathogens: Investigating the Prospect of Testing a Representative Drug for Each Antimicrobial Family
(MDPI, 2022-05-10)
Antimicrobial susceptibility testing is necessary to carry out antimicrobial stewardship but a limited number of drugs belonging to each antimicrobial family has to be tested for technical limitations ...
Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target [version 1; peer review: awaiting peer review]
(F1000Research, 2020-01-27)
A novel coronavirus recently identified in Wuhan, China (2019-nCoV) has
expanded the number of highly pathogenic coronaviruses affecting
humans. The 2019-nCoV represents a potential epidemic or ...
Alteration in the Culex pipiens transcriptome reveals diverse mechanisms of the mosquito immune system implicated upon Rift Valley fever phlebovirus exposure
(Public Library of Science, 2020-12-10)
Rift Valley fever phlebovirus (RVFV) causes an emerging zoonotic disease and is mainly transmitted by Culex and Aedes mosquitoes. While Aedes aegypti-dengue virus (DENV) is the most studied model, less ...
Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquito Culex pipiens
(Oxford University Press, 2023-08-24)
Our knowledge of the diversity of eukaryotic viruses has recently undergone a massive expansion. This diversity could infuence host
physiology through yet unknown phenomena of potential interest to the ...
West Nile Virus Lineage 2 Spreads Westwards in Europe and Overwinters in North-Eastern Spain (2017–2020)
(MDPI, 2022-03-09)
West Nile virus lineage 2 (WNV-L2) emerged in Europe in 2004; since then, it has spread across the continent, causing outbreaks in humans and animals. During 2017 and 2020, WNV-L2 was detected and ...
Zika vector competence data reveals risks of outbreaks: the contribution of the European ZIKAlliance project
(Nature Research, 2022-08-02)
First identified in 1947, Zika virus took roughly 70 years to cause a pandemic unusually associated with virus-induced brain damage in newborns. Zika virus is transmitted by mosquitoes, mainly Aedes ...
Chicken liver is a potential reservoir of bacteriophages and phage-derived particles containing antibiotic resistance genes
(Wiley Open Access, 2022-04-29)
Poultry meat production is one of the most important agri-food industries in the world. The selective pressure exerted by widespread prophylactic or therapeutic use of antibiotics in intensive chicken ...
Identification of African Swine Fever Virus Transcription within Peripheral Blood Mononuclear Cells of Acutely Infected Pigs
(MDPI, 2021-11-22)
African swine fever virus (ASFV) has become widespread in Europe, Asia and elsewhere, thereby causing extensive economic losses. The viral genome includes nearly 200 genes, but their expression within ...
Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
(Elsevier, 2021-09-21)
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the ...