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Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infection
(BMC, 2022-09-02)
Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to public health. Here, we established an ex vivo alpaca tracheal explant (ATE) model using an air-liquid interface culture ...
Modeling the impact of surveillance activities combined with physical distancing interventions on COVID-19 epidemics at a local level
(KeAi Communications, 2022-11-17)
Physical distancing and contact tracing are two key components in controlling the COVID-
19 epidemics. Understanding their interaction at local level is important for policymakers.
We propose a flexible ...
Assessing the role of livestock and sympatric wild ruminants in spreading antimicrobial resistant Campylobacter and Salmonella in alpine ecosystems
(BMC, 2021-02-15)
Background: Livestock play an important role as reservoir of enteric pathogens and antimicrobial resistance (AMR), a health and economic concern worldwide. However, little is known regarding the ...
About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
(BMC, 2019-06-24)
Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to
understand how gene expression is genetically regulated in a context-dependent manner. In ...
Exploratory field study on the effects of porcine circovirus 2 (PCV-2) sow vaccination at different physiological stages mimicking blanket vaccination
(BMC, 2021-04-26)
Background: The objective of the present study was to explore the benefits of Porcine circovirus 2 (PCV-2) blanket vaccination in a sow herd on productive parameters, PCV-2 infection and immune status ...
Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant
(Frontiers Media, 2023-12-04)
Most COVID-19 vaccines are based on the SARS-CoV-2 Spike glycoprotein (S) or
their subunits. However, S shows some structural instability that limits its
immunogenicity and production, hampering the ...
Understanding host-microbiota interactions in the commercial piglet around weaning
(Nature Research, 2021-12-06)
Weaning is a critical period in the life of pigs with repercussions on their health and welfare and on the
economy of the swine industry. This study aimed to assess the efect of the commercial early ...
First identification and characterization of ovine gammaherpesvirus type 2 in horses and artiodactyla from an outbreak of malignant catarrhal fever in Mexico
(Public Library of Science, 2023-09-01)
Ovine gammaherpesvirus 2 (OvHV-2), a member of the genus Macavirus, causes sheepassociated malignant catarrhal fever (SA-MCF), a fatal lymphoproliferative disease affecting
a wide variety of ungulates ...
The feather epithelium contributes to the dissemination and ecology of clade 2.3.4.4b H5 high pathogenicity avian influenza viruses in ducks
(Taylor and Francis, 2023-11-03)
Immature feathers are known replication sites for high pathogenicity avian influenza viruses (HPAIVs) in poultry.
However, it is unclear whether feathers play an active role in viral transmission. This ...
Heterologous Systemic Prime–Intranasal Boosting Using a Spore SARS-CoV-2 Vaccine Confers Mucosal Immunity and Cross-Reactive Antibodies in Mice as well as Protection in Hamsters
(MDPI, 2022-11-10)
Background: Current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are administered systemically and typically result in poor immunogenicity at the mucosa. As a result, vaccination ...