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kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
High sensitivity of one-step real-time reverse transcription quantitative PCR to detect low virus titers in large mosquito pools
(BMC, 2020-09-09)
Background: Mosquitoes are the deadliest animals in the world. Their ability to carry and spread diseases to humans causes millions of deaths every year. Due to the lack of efficient vaccines, the control ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...
High-Resolution Profiling of Innate Immune Responses by Porcine Dendritic Cell Subsets in vitro and in vivo
(Frontiers Media, 2020-07-07)
The present study investigated the transcriptomic response of porcine dendritic cells (DC) to innate stimulation in vitro and in vivo. The aim was to identify DC subset-specialization, suitable Toll-like ...
Prevalence of Salmonella in Free-Range Pigs: Risk Factors and Intestinal Microbiota Composition
(MDPI, 2021-06-18)
Extensive pig systems are gaining importance as quality production systems and as the standard for sustainable rural development and animal welfare. However, the effects of natural foods on Salmonella ...
Influence of dietary n-3 long-chain fatty acids on microbial diversity and composition of sows’ feces, colostrum, milk, and suckling piglets’ feces
(Frontiers Media, 2022-12-05)
Introduction: Very little is known about the impact of n-3 long-chain fatty acids (n-3 LCFAs) on the microbiota of sows and their piglets. The aim of this study was to evaluate the effect of n-3 LCFA ...
African swine fever vaccines: a promising work still in progress
(BMC, 2020-07-02)
African swine fever (ASF), a disease of obligatory declaration to the World Organization for Animal Health (OIE), has contributed to poverty and underdevelopment of affected areas. The presence of ASF ...
Immune Responses to Pandemic H1N1 Influenza Virus Infection in Pigs Vaccinated with a Conserved Hemagglutinin HA1 Peptide Adjuvanted with CAF®01 or CDA/αGalCerMPEG
(MDPI, 2021-07-06)
This study aimed to evaluate the immune response and protection correlates against influenza virus (IV) infection in pigs vaccinated with the novel NG34 HA1 vaccine candidate adjuvanted with either ...
Descriptive analyses of maternally-derived antibody levels against porcine circovirus 2 (PCV-2) in 3-and 21-day-old piglets from farms of four European countries using different vaccination protocols in sows
(BMC, 2022-10-03)
Background
Up to now, information on the levels of maternally-derived antibodies (MDA) against PCV-2 in suckling piglets born to sows vaccinated with different strategies is scarce in the literature. ...
Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein
(Taylor & Francis Open, 2019-11-12)
The ongoing Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks pose a worldwide public health threat. Blocking MERS-CoV zoonotic transmission from dromedary camels, the animal reservoir, ...