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Feeding Spray-Dried Porcine Plasma to Pigs Improves the Protection Afforded by the African Swine Fever Virus (ASFV) BA71∆CD2 Vaccine Prototype against Experimental Challenge with the Pandemic ASFV—Study 2
(MDPI, 2023-04-10)
This study aimed to evaluate the effects of feeding spray-dried porcine plasma (SDPP) on the protection afforded by the BA71∆CD2 African swine fever virus (ASFV) vaccine prototype. Two groups of pigs ...
Enhanced antiviral immunity and dampened inflammation in llama lymph nodes upon MERS-CoV sensing: bridging innate and adaptive cellular immune responses in camelid reservoirs
(Frontiers Media, 2023-06-14)
Middle East respiratory syndrome coronavirus (MERS-CoV) infection can cause fatal pulmonary inflammatory disease in humans. Contrarily, camelids and bats are the main reservoir hosts, tolerant for ...
Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies
(Wiley, 2020-10-02)
Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through different routes, including intranasal, intratracheal, intramuscular and intravenous ones. ...
Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health
(American Association for the Advancement of Science, 2021-03-31)
Accelerated postnatal growth is a potentially modifiable risk factor for future obesity. To study how specific breast milk components contribute to early growth and obesity risk, we quantified one-carbon ...
DNA vaccine based on conserved HA-peptides induces strong immune response and rapidly clears influenza virus infection from vaccinated pigs
(Public Library of Science, 2019-09-25)
Swine influenza virus (SIVs) infections cause a significant economic impact to the pork industry.
Moreover, pigs may act as mixing vessel favoring genome reassortment of diverse influenza
viruses. ...
β-Cyclodextrins as affordable antivirals to treat coronavirus infection
(Elsevier, 2023-06-08)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. ...
Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target [version 1; peer review: awaiting peer review]
(F1000Research, 2020-01-27)
A novel coronavirus recently identified in Wuhan, China (2019-nCoV) has
expanded the number of highly pathogenic coronaviruses affecting
humans. The 2019-nCoV represents a potential epidemic or ...
Identification of microRNAs in PCV2 subclinically infected pigs by high throughput sequencing
(BMC, 2015-03-03)
Porcine circovirus type 2 (PCV2) is the essential etiological infectious agent of PCV2-systemic disease and has been associated with other swine diseases, all of them collectively known as porcine ...
Diagnosis by ruling out other diseases or conditions
(BMJ Publishing Group, 2018-07-19)
Pig production is nowadays highly specialised, and is dominated by large, intensive, indoor-rearing production systems around the world. As farming systems have evolved, so also has our understanding ...
SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity
(Nature Research, 2021-01-28)
The protective effect of neutralizing antibodies in SARS-CoV-2 infected individuals is not yet well defined. To address this issue, we have analyzed the kinetics of neutralizing antibody responses and ...