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β-Cyclodextrins as affordable antivirals to treat coronavirus infection
(Elsevier, 2023-06-08)
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. ...
Modelling the spatial risk of malaria through probability distribution of Anopheles maculipennis s.l. and imported cases
(Taylor and Francis, 2024-05-02)
Malaria remains one of the most important infectious diseases globally due to its high incidence and mortality rates. The
influx of infected cases from endemic to non-endemic malaria regions like Europe ...
Navigating through space and time: A methodological approach to quantify spatiotemporal connectivity using stream flow data as a case study
(Wiley, 2023-05-16)
1. The growing interest in combining spatial and temporal patterns in nature has been fostered by the current availability of high-frequency measurements. However, we still lack a methodological framework ...
cmv1-Mediated Resistance to CMV in Melon Can Be Overcome by Mixed Infections with Potyviruses
(MDPI, 2023-08-23)
Resistance to cucumber mosaic virus (CMV) strain LS in melon is controlled by the gene cmv1, which restricts phloem entry. In nature, CMV is commonly found in mixed infections, particularly with ...
Aquaporin splice variation differentially modulates channel function during marine teleost egg hydration
(Public Library of Science, 2023-11-27)
Aquaporin-mediated oocyte hydration is a developmentally regulated adaptive mechanism that co-occurs with meiosis resumption in marine teleosts. It provides the early embryos with vital water until ...
Understanding the key features of the spontaneous formation of bona fde prions through a novel methodology that enables their swift and consistent generation
(BMC, 2023-09-07)
Among transmissible spongiform encephalopathies or prion diseases afecting humans, sporadic forms such as spo‑
radic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms ...
Modeling the airborne inoculum of Polystigma amygdalinum to optimize fungicide programs against almond red leaf blotch
(American Phytopathological Society, 2023-09-27)
Red leaf blotch (RLB) of almond, caused by the ascomycete Polystigma amygdalinum, is a severe foliar disease endemic in the Mediterranean Basin and Middle East regions. Airborne ascospores of P. amygdalinum ...
Endogenous CO2 Overpressure Effect on Higher Alcohols Metabolism during Sparkling Wine Production
(MDPI, 2023-06-22)
Higher alcohols produced by yeast during the fermentation of sparkling wine must have the greatest impact on the smell and taste of wine. At present, the metabolic response to methanol and higher alcohols ...
Mutations in CmVPS41 controlling resistance to cucumber mosaic virus display specific subcellular localization
(Oxford University Press, 2022-12-17)
Resistance to cucumber mosaic virus (CMV) in melon (Cucumis melo L.) has been described in several exotic accessions and is controlled by a recessive resistance gene, cmv1, that encodes a vacuolar protein ...
Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs
(Oxford University Press, 2023-03-22)
Aquaporin-mediated oocyte hydration is considered important for the evolution of pelagic eggs and the radiative success of marine teleosts. However, the molecular regulatory mechanisms controlling this ...