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Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
(Nature Research, 2016-08-18)
The aim of this work is to better understand the genetic mechanisms determining two complex traits
affecting porcine meat quality: intramuscular fat (IMF) content and its fatty acid (FA) composition. ...
Transcriptional Characterization of Porcine Leptin and Leptin Receptor Genes
(Public Library of Science, 2013-06-18)
The leptin (LEP) and its receptor (LEPR) regulate food intake and energy balance through hypothalamic signaling. However, the LEP-LEPR axis seems to be more complex and its expression regulation has not ...
Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs
(Public Library of Science, 2019-06-27)
The selection in commercial swine breeds for meat-production efficiency has been increasing among the past decades, reducing the intramuscular fat content, which has changed the sensorial and technological ...
Diversity across major and candidate genes in European local pig breeds
(Public Library of Science, 2018-11-20)
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...
Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed
(PLoS ONE, 2018-03-09)
One of the major limitation for the application of QTL results in pig breeding and QTN identification has been the limited number of QTL effects validated in different animal material. The aim
of the ...
Genomic diversity, linkage disequilibrium and selection signatures in European local pig breeds assessed with a high density SNP chip
(Nature Research, 2019-09-19)
Genetic characterization of local breeds is essential to preserve their genomic variability, to advance conservation policies and to contribute to their promotion and sustainability. Genomic diversity ...
Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles
(BMC, 2019-03-04)
Background
Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns ...
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
(Springer Nature, 2018-08-28)
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its physiological similarities. The aim of this study was to describe the ...
Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits
(Nature Research, 2017-01-05)
Meat quality traits have an increasing importance in the pig industry because of their strong impact on
consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to ...
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
(Nature Research, 2017-04-19)
In the present study, liver co-expression networks and expression Genome Wide Association Study
(eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional
regulatory ...