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Association between the pig genome and its gut microbiota composition
(Nature Research, 2019-06-19)
The gut microbiota has been evolving with its host along the time creating a symbiotic relationship. In this study, we assess the role of the host genome in the modulation of the microbiota composition ...
Leveraging host-genetics and gut microbiota to determine immunocompetence in pigs
(BMC, 2021-10-24)
Background: The gut microbiota infuences host performance playing a relevant role in homeostasis and function of
the immune system. The aim of the present work was to identify microbial signatures ...
Early socialization and environmental enrichment of lactating piglets affects the caecal microbiota and metabolomic response after weaning
(Nature Research, 2021-03-17)
The aim of this study was to determine the possible impact of early socialization and an enriched neonatal environment to improve adaptation of piglets to weaning. We hypothesized that changes in the ...
Integration of GWAS, pathway and network analyses reveals novel mechanistic insights into the synthesis of milk proteins in dairy cows
(Nature Research, 2018-01-12)
The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, ...
Five genomic regions have a major impact on fat composition in Iberian pigs
(Nature Research, 2019-02-14)
The adipogenic nature of the Iberian pig defines many quality attributes of its fresh meat and dry-cured products. The distinct varieties of Iberian pig exhibit great variability in the genetic parameters ...
Malignant infarction of the middle cerebral artery in a porcine model. A pilot study
(Public Library of Science, 2017-02-24)
Background and purpose. Interspecies variability and poor clinical translation from rodent studies indicate that large gyrencephalic animal stroke models are urgently needed. We present a proof-of-principle ...
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources
(Nature Research, 2021-02-09)
Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral ...
kernInt: A Kernel Framework for Integrating Supervised and Unsupervised Analyses in Spatio-Temporal Metagenomic Datasets
(Frontiers Media, 2021-01-28)
The advent of next-generation sequencing technologies allowed relative quantification of microbiome communities and their spatial and temporal variation. In recent years, supervised learning (i.e., ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...
Influence of dietary n-3 long-chain fatty acids on microbial diversity and composition of sows’ feces, colostrum, milk, and suckling piglets’ feces
(Frontiers Media, 2022-12-05)
Introduction: Very little is known about the impact of n-3 long-chain fatty acids (n-3 LCFAs) on the microbiota of sows and their piglets. The aim of this study was to evaluate the effect of n-3 LCFA ...