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Removal of the Erns RNase Activity and of the 39 Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease
(American Society for Microbiology, 2022-06-27)
In this study, we assessed the potential synergistic effect of the Erns RNase activity and the poly-U insertion in the 3′ untranslated region (UTR) of the low-virulence classical swine fever virus (CSFV) ...
A neutralizing monoclonal antibody-based competitive ELISA for classical swine fever C-strain post–vaccination monitoring
(BMC, 2020-01-14)
Background: Virus neutralization test (VNT) is widely used for serological survey of classical swine fever (CSF) and efficacy evaluation of CSF vaccines. However, VNT is a time consuming procedure that ...
Investigation of chronic and persistent classical swine fever infections under field conditions and their impact on vaccine efficacy
(BMC, 2019-07-15)
Background: Recent studies have hypothesized that circulation of classical swine fever virus (CSFV) variants when the immunity induced by the vaccine is not sterilizing might favour viral persistence. ...
Evaluation of a Phylogenetic Marker Based on Genomic Segment B of Infectious Bursal Disease Virus: Facilitating a Feasible Incorporation of this Segment to the Molecular Epidemiology Studies for this Viral Agent
(Public Library of Science, 2015-05-06)
Background
Infectious bursal disease (IBD) is a highly contagious and acute viral disease, which has caused high mortality rates in birds and considerable economic losses in different parts of the world ...
Evolution of Swine Influenza Virus H3N2 in Vaccinated and Nonvaccinated Pigs after Previous Natural H1N1 Infection
(MDPI, 2022-09-10)
Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed
disease that can cause important economic losses to the pig industry. Currently, this virus is endemic
in farms and, ...
Multi-Target Strategy for Pan/Foot-and-Mouth Disease Virus (FMDV) Detection: A Combination of Sequences Analysis, in Silico Predictions and Laboratory Diagnostic Evaluation
(Frontiers Media, 2018-07-12)
Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals that causes severe economic losses. The disease is characterized by a vesicular condition and it cannot ...
Development of a Dendrimeric Peptide-Based Approach for the Differentiation of Animals Vaccinated with FlagT4G against Classical Swine Fever from Infected Pigs
(MDPI, 2021-10-02)
Classical swine fever virus (CSFV) causes a viral disease of high epidemiological and
economical significance that affects domestic and wild swine. Control of the disease in endemic
countries is based ...
2023 International African Swine Fever Workshop: Critical Issues That Need to Be Addressed for ASF Control
(MDPI, 2023-12-19)
The 2023 International African Swine Fever Workshop (IASFW) took place in Beijing,
China, on 18–20 September 2023. It was jointly organized by the U.S.-China Center for Animal
Health (USCCAH) at Kansas ...
Efficient detection of African Swine Fever Virus using minimal equipment through a LAMP PCR method
(Frontiers Media, 2023-01-27)
African swine fever virus (ASFV) currently represents the biggest threat to the porcine industry worldwide, with high economic impact and severe animal health and welfare concerns. Outbreaks have occurred ...
A Polyuridine Insertion in the 3′ Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets
(American Society for Microbiology, 2020-01-06)
Low-virulence classical swine fever virus (CSFV) strains make CSF eradication particularly difficult. Few data are available on the molecular determinants of CSFV virulence. The aim of the present study ...