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Examining the cooperativity mode of antibody and CD8+ T cell immune responses for vaccinology
(Elsevier, 2021-09-21)
A fundamental unsolved issue in vaccine design is how neutralizing antibodies and cytotoxic CD8+ T cells cooperate numerically in controlling virus infections. We hypothesize on a viewpoint for the ...
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie
(Nature Research, 2021-08-31)
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the ...
Comparison of cytokine profiles in peripheral blood mononuclear cells between piglets born from Porcine circovirus 2 vaccinated and non-vaccinated sows
(Elsevier, 2017-12-19)
This study was aimed to evaluate the effect of Porcine circovirus 2 (PCV2) sow vaccination on cell-mediated immune responses in sows and their progeny. At 7 weeks before farrowing, fifteen PCV2 PCR ...
Increasing breast milk betaine modulates Akkermansia abundance in mammalian neonates and improves long-term metabolic health
(American Association for the Advancement of Science, 2021-03-31)
Accelerated postnatal growth is a potentially modifiable risk factor for future obesity. To study how specific breast milk components contribute to early growth and obesity risk, we quantified one-carbon ...
Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status
(BMC, 2024-01-16)
Background Porcine circovirus 2 (PCV‑2) poses a signifcant economic threat for the swine industry, causing a range
of diseases collectively referred to as porcine circovirus diseases (PCVDs). Despite ...
Experimental study of the susceptibility of a European Aedes albopictus strain to dengue virus under a simulated Mediterranean temperature regime
(Wiley, 2018-07-27)
Dengue virus (DENV) has re‐emerged in Europe driven by the geographic expansion of the mosquito species Aedes albopictus and Aedes aegypti (Diptera: Culicidae) and the introduction of the virus by ...
Gut‑associated microbes are present and active in the pig nasal cavity
(Nature Research, 2024-04-11)
The nasal microbiota is a key contributor to animal health, and characterizing the nasal microbiota
composition is an important step towards elucidating the role of its diferent members. Eforts ...
Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena
(Elsevier, 2020-06-02)
Porcine reproductive and respiratory syndrome virus (PRRSV) plays a key role in porcine respiratory disease complex modulating the host immune response and favouring secondary bacterial infections. ...
Exploratory Study of the Frequency of Detection and Tissue Distribution of Porcine Circovirus 3 (PCV-3) in Pig Fetuses at Different Gestational Ages
(MDPI, 2022-01-20)
Porcine circovirus 3 (PCV-3) has been associated with several pig diseases. Despite the pathogenicity of this virus has not been completely clarified, reproductive disorders are consistently associated ...
Assessing the variability in transmission of bovine tuberculosis within Spanish cattle herds
(Elsevier, 2018-01-31)
In Spain, despite years of efforts to eradicate bovine tuberculosis (bTB), the disease is still endemic, with some
areas of high prevalence. In this context, the surveillance and control plans may need ...