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Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits
(Elsevier, 2023-02-24)
In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is ...
Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits
(Nature Research, 2017-01-05)
Meat quality traits have an increasing importance in the pig industry because of their strong impact on
consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to ...
Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles
(BMC, 2018-02-14)
Background: The identification of genes differentially expressed in the skeletal muscle of pigs displaying distinct
growth and fatness profiles might contribute to identify the genetic factors that ...
A gene co-association network regulating gut microbial communities in a Duroc pig population
(BMC, 2021-02-21)
Background. Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic ...
About the existence of common determinants of gene expression in the porcine liver and skeletal muscle
(BMC, 2019-06-24)
Background: The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to
understand how gene expression is genetically regulated in a context-dependent manner. In ...
Genomic architecture of carcass and pork traits and their association with immune capacity
(Elsevier, 2023-11-28)
Carcass and pork traits have traditionally been considered of prime importance in pig breeding programmes. However, the changing conditions in modern farming, coupled with antimicrobial resistance issues, ...
Diversity across major and candidate genes in European local pig breeds
(Public Library of Science, 2018-11-20)
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds. Also, the potential of the SNP panel ...
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
(MDPI, 2024-01-26)
Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by ...
Integrating genome-wide co-association and gene expression to identify putative regulators and predictors of feed efficiency in pigs
(BMC, 2019-09-02)
Background: Feed efciency (FE) has a major impact on the economic sustainability of pig production. We used a
systems‑based approach that integrates single nucleotide polymorphism (SNP) co‑association ...
A Co-Association Network Analysis Reveals Putative Regulators for Health-Related Traits in Pigs
(Frontiers Media, 2021-11-26)
In recent years, the increase in awareness of antimicrobial resistance together with the societal demand of healthier meat products have driven attention to health-related traits in livestock production. ...