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African swine fever vaccines: a promising work still in progress
(BMC, 2020-07-02)
African swine fever (ASF), a disease of obligatory declaration to the World Organization for Animal Health (OIE), has contributed to poverty and underdevelopment of affected areas. The presence of ASF ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...
Experimental Inoculation of Porcine Circovirus 3 (PCV-3) in Pregnant Gilts Causes PCV-3-Associated Lesions in Newborn Piglets that Persist until Weaning
(Wiley, 2023-10-20)
Porcine circovirus 3 (PCV-3) has been detected in cases of reproductive failure but the pathogenesis of such infection is poorly
understood. So far, experimental PCV-3 inoculations have been performed ...
The analysis of genome composition and codon bias reveals distinctive patterns between avian and mammalian circoviruses which suggest a potential recombinant origin for Porcine circovirus 3
(Public Library of Science, 2018-06-29)
Members of the genus Circovirus are host-specific viruses, which are totally dependent on cell machinery for their replication. Consequently, certain mimicry of the host genome features is expected to ...
Five genomic regions have a major impact on fat composition in Iberian pigs
(Nature Research, 2019-02-14)
The adipogenic nature of the Iberian pig defines many quality attributes of its fresh meat and dry-cured products. The distinct varieties of Iberian pig exhibit great variability in the genetic parameters ...
Histopathological and virological findings in emaciated pigs from Mexico: an exploratory study
(University of Veterinary and Pharmaceutical Sciences, Brno, 2018-06-27)
The objective of this work was to detect the presence of three main pig respiratory viral agents
(porcine rubulavirus [PorPV], porcine circovirus type 2 [PCV-2], and porcine reproductive and
respiratory ...
ICTV Virus Taxonomy Profile: Asfarviridae
(Microbiology Society, 2018-03-22)
The family Asfarviridae includes the single species African swine fever virus, isolates of which have linear dsDNA genomes of
170–194 kbp. Virions have an internal core, an internal lipid membrane, an ...
Mixtures of prion substrains in natural scrapie cases revealed by ovinised murine models
(Nature Research, 2020-03-19)
Phenotypic variability in prion diseases, such as scrapie, is associated to the existence of prion strains, which are different pathogenic prion protein (PrPSc) conformations with distinct pathobiological ...
Efficacy of novel recombinant fowlpox vaccine against recent Mexican H7N3 highly pathogenic avian influenza virus
(Elsevier, 2019-03-15)
Since 2012, H7N3 highly pathogenic avian influenza (HPAI) has produced negative economic and animal welfare impacts on poultry in central Mexico. In the present study, chickens were vaccinated with two ...
Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4
(Nature Research, 2018-06-27)
Middle East respiratory syndrome (MERS) represents an important respiratory disease accompanied by lethal outcome in one-third of human patients. Recent data indicate that dromedaries represent an ...