Search
Now showing items 1-4 of 4
An association analysis between a polymorphism in the SEC24A gene and lipid traits recorded in Duroc pigs
(Taylor & Francis Open Access, 2021-10-05)
By regulating the expression of low-density lipoprotein receptors (LDLR), the SEC24A protein modulates the clearance of plasma cholesterol in mice. The whole-genome sequencing of five Duroc boars that ...
Modeling microRNA-driven post-transcriptional regulation using exon–intron split analysis in pigs
(Wiley, 2022-07-10)
The contribution of microRNAs (miRNAs) to mRNA post-transcriptional regulation has often been explored by the post hoc selection of downregulated genes and determining whether they harbor binding sites ...
Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes
(BMC, 2021-05-04)
Background: Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of
mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding ...
Assessing the relationship between the in silico predicted consequences of 97 missense mutations mapping to 68 genes related to lipid metabolism and their association with porcine fatness traits
(Elsevier, 2023-02-24)
In general, the relationship between the predicted functional consequences of missense mutations mapping to genes known to be involved in human diseases and the severity of disease manifestations is ...