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dc.contributor.authorRodríguez-Valera, Yoel
dc.contributor.authorRocha, Dominique
dc.contributor.authorNaves, Michel
dc.contributor.authorRenand, Gilles
dc.contributor.authorPérez-Pineda, Eliecer
dc.contributor.authorRamayo-Caldas, Yuliaxis
dc.contributor.authorRamos-Onsins, Sebastian E.
dc.contributor.otherProducció Animalca
dc.date.accessioned2021-02-25T13:58:00Z
dc.date.available2021-02-25T13:58:00Z
dc.date.issued2020-11-27
dc.identifier.citationRodríguez-Valera, Yoel, Dominique Rocha, Michel Naves, Gilles Renand, Eliecer Pérez-Pineda, Yuliaxis Ramayo-Caldas, and Sebastian E. Ramos-Onsins. 2020. "The Identification Of Runs Of Homozygosity Gives A Focus On The Genetic Diversity And Adaptation Of The “Charolais De Cuba” Cattle". Animals 10 (12): 2233. doi:10.3390/ani10122233.ca
dc.identifier.issn2076-2615ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/1159
dc.description.abstractInbreeding and effective population size (Ne) are fundamental indicators for the management and conservation of genetic diversity in populations. Genomic inbreeding gives accurate estimates of inbreeding, and the Ne determines the rate of the loss of genetic variation. The objective of this work was to study the distribution of runs of homozygosity (ROHs) in order to estimate genomic inbreeding (FROH) and an effective population size using 38,789 Single Nucleotide Polymorphisms (SNPs) from the Illumina Bovine 50K BeadChip in 86 samples from populations of Charolais de Cuba (n = 40) cattle and to compare this information with French (n = 20) and British Charolais (n = 26) populations. In the Cuban, French, and British Charolais populations, the average estimated genomic inbreeding values using the FROH statistics were 5.7%, 3.4%, and 4%, respectively. The dispersion measured by variation coefficient was high at 43.9%, 37.0%, and 54.2%, respectively. The effective population size experienced a very similar decline during the last century in Charolais de Cuba (from 139 to 23 individuals), in French Charolais (from 142 to 12), and in British Charolais (from 145 to 14) for the ~20 last generations. However, the high variability found in the ROH indicators and FROH reveals an opportunity for maintaining the genetic diversity of this breed with an adequate mating strategy, which can be favored with the use of molecular markers. Moreover, the detected ROH were compared to previous results obtained on the detection of signatures of selection in the same breed. Some of the observed signatures were confirmed by the ROHs, emphasizing the process of adaptation to tropical climate experienced by the Charolais de Cuba population.ca
dc.format.extent16ca
dc.language.isoengca
dc.publisherMDPIca
dc.relation.ispartofAnimalsca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleThe Identification of Runs of Homozygosity Gives a Focus on the Genetic Diversity and Adaptation of the “Charolais de Cuba” Cattleca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.relation.projectIDMINECO/Programa Estatal de fomento de la investigación científica y técnica de excelencia/SEV-2015-0533/ES/ /ca
dc.relation.projectIDEC/H2020/665919/EU/Opening Sphere UAB-CEI to PostDoctoral Fellows/P-SPHEREca
dc.relation.projectIDMINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2013-41834-R/ES/HERRAMIENTAS DE NUEVA GENERACION PARA EXPLOTAR LA DIVERSIDAD DE LAS ESPECIES DOMESTICAS/ca
dc.relation.projectIDMINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2016-78709-R/ES/UTILIZACION DE SECUENCIAS COMPLETAS PARA LA MEJORA DE ESPECIES DOMESTICAS/ca
dc.subject.udc619ca
dc.identifier.doihttps://doi.org/10.3390/ani10122233ca
dc.contributor.groupGenètica i Millora Animalca


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