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dc.contributor.authorObradovic, Milan R.
dc.contributor.authorSegura, Mariela
dc.contributor.authorSegalés, Joaquim
dc.contributor.authorGottschalk, Marcelo
dc.contributor.otherProducció Animalca
dc.date.accessioned2021-06-07T12:43:20Z
dc.date.available2021-06-07T12:43:20Z
dc.date.issued2021-03-20
dc.identifier.citationObradovic, Milan R., Mariela Segura, Joaquim Segalés, and Marcelo Gottschalk. 2021. "Review Of The Speculative Role Of Co-Infections In Streptococcus Suis-Associated Diseases In Pigs". Veterinary Research 52 (1). doi:10.1186/s13567-021-00918-w.ca
dc.identifier.issn0928-4249ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/1282
dc.description.abstractStreptococcus suis is one of the most important bacterial swine pathogens affecting post-weaned piglets, causing mainly meningitis, arthritis and sudden death. It not only results in severe economic losses but also raises concerns over animal welfare and antimicrobial resistance and remains an important zoonotic agent in some countries. The definition and diagnosis of S. suis-associated diseases can be complex. Should S. suis be considered a primary or secondary pathogen? The situation is further complicated when referring to respiratory disease, since the pathogen has historically been considered as a secondary pathogen within the porcine respiratory disease complex (PRDC). Is S. suis a respiratory or strictly systemic pathogen? S. suis is a normal inhabitant of the upper respiratory tract, and the presence of potentially virulent strains alone does not guarantee the appearance of clinical signs. Within this unclear context, it has been largely proposed that co-infection with some viral and bacterial pathogens can significantly influence the severity of S. suis-associated diseases and may be the key to understanding how the infection behaves in the field. In this review, we critically addressed studies reporting an epidemiological link (mixed infections or presence of more than one pathogen at the same time), as well as in vitro and in vivo studies of co-infection of S. suis with other pathogens and discussed their limitations and possibilities for improvement and proposed recommendations for future studies.ca
dc.format.extent22ca
dc.language.isoengca
dc.publisherBMCca
dc.relation.ispartofVeterinary Researchca
dc.rightsAttribution 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleReview of the speculative role of co-infections in Streptococcus suis-associated diseases in pigsca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.subject.udc619ca
dc.identifier.doihttps://doi.org/10.1186/s13567-021-00918-wca
dc.contributor.groupSanitat Animalca


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