Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 3: Amprolium
Autor/a
EFSA Panel on Biological Hazards (BIOHAZ)
Koutsoumanis, Konstantinos
Allende, Ana
Alvarez-Ordóñez, Avelino
Bolton, Declan
Chemaly, Marianne
Davies, Robert
De Cesare, Alessandra
Herman, Lieve
Hilbert, Friederike
Lindqvist, Roland
Nauta, Maarten
Ru, Giuseppe
Simmons, Marion
Skandamis, Panagiotis
Suffredini, Elisabetta
Andersson, Dan I
Bampidis, Vasileios
Bengtsson-Palme, Johan
Bouchard, Damien
Ferran, Aude
Kouba, Maryline
López Puente, Secundino
López-Alonso, Marta
Nielsen, Søren Saxmose
Pechová, Alena
Petkova, Mariana
Girault, Sebastien
Broglia, Alessandro
Guerra, Beatriz
Innocenti, Matteo Lorenzo
Liébana, Ernesto
López-Gálvez, Gloria
Manini, Paola
Stella, Pietro
Peixe, Luisa
Fecha de publicación
2021-10-26ISSN
1831-4732
Resumen
The specific concentrations of amprolium in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC for amprolium, it was not possible to conclude the assessment. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. Levels of amprolium in feed that showed to have an effect on growth promotion/increased yield were reported. The lack of antibacterial activity at clinically relevant concentrations for amprolium suggests that further studies relating to bacterial resistance are not a priority.
Tipo de documento
Artículo
Versión del documento
Versión publicada
Lengua
English
Materias (CDU)
663/664 - Alimentos y nutrición. Enología. Aceites. Grasas
Páginas
20
Publicado por
Wiley Open Access
Publicado en
EFSA Journal
Citación
Koutsoumanis, Konstantinos, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, and Robert Davies et al. 2021. "Maximum Levels Of Cross‐Contamination For 24 Antimicrobial Active Substances In Non‐Target Feed. Part 3: Amprolium". EFSA Journal 19 (10). doi:10.2903/j.efsa.2021.6854.
Program
Funcionalitat i Seguretat Alimentària
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