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Porcine circovirus 3 (PCV-3) as a causal agent of disease in swine and a proposal of PCV-3 associated disease case definition
dc.contributor.author | Saporiti, Viviane | |
dc.contributor.author | Franzo, Giovanni | |
dc.contributor.author | Sibila, Marina | |
dc.contributor.author | Segalés, Joaquim | |
dc.contributor.other | Producció Animal | ca |
dc.date.accessioned | 2022-01-20T13:00:44Z | |
dc.date.available | 2022-01-20T13:00:44Z | |
dc.date.issued | 2021-06-29 | |
dc.identifier.citation | Saporiti, Viviane, Giovanni Franzo, Marina Sibila, and Joaquim Segalés. 2021. "Porcine Circovirus 3 (PCV‐3) As A Causal Agent Of Disease In Swine And A Proposal Of PCV‐3 Associated Disease Case Definition". Transboundary And Emerging Diseases 68 (6): 2936-2948. doi:10.1111/tbed.14204. | ca |
dc.identifier.issn | 1865-1674 | ca |
dc.identifier.uri | http://hdl.handle.net/20.500.12327/1500 | |
dc.description.abstract | Porcine circovirus 3 (PCV-3) was discovered in 2015 using next-generation sequencing (NGS) methods. Since then, the virus has been detected worldwide in pigs displaying several clinical-pathological outcomes as well as in healthy animals. The objective of this review is to critically discuss the evidence existing so far regarding PCV-3 as a swine pathogen. In fact, a significant number of publications claim PCV-3 as a disease causal infectious agent, but very few of them have shown strong evidence of such potential causality. The most convincing proofs of disease association are those that demonstrate a clinical picture linked to multisystemic lymphoplasmacytic to lymphohistiocytic perivascular inflammation and presence of viral nucleic acid within these lesions. Based on these evidence, individual case definitions for PCV-3-reproductive disease and PCV-3-systemic disease are proposed to standardize diagnostic criteria for PCV-3-associated diseases. However, the real frequency of these clinical-pathological conditions linked to the novel virus is unknown, and the most frequent outcome of PCV-3 infection is likely subclinical based on its worlwide distribution. | ca |
dc.format.extent | 13 | ca |
dc.language.iso | eng | ca |
dc.publisher | Wiley | ca |
dc.relation.ispartof | Transboundary and Emerging Diseases | ca |
dc.rights | Attribution-NonCommercial 4.0 International | ca |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.title | Porcine circovirus 3 (PCV-3) as a causal agent of disease in swine and a proposal of PCV-3 associated disease case definition | ca |
dc.type | info:eu-repo/semantics/article | ca |
dc.description.version | info:eu-repo/semantics/publishedVersion | ca |
dc.rights.accessLevel | info:eu-repo/semantics/openAccess | |
dc.embargo.terms | cap | ca |
dc.relation.projectID | MINECO/Programa estatal de I+D+I orientada a los retos de la sociedad/E-RTA2017-00007-00-00/ES/Impacto de la infección por un nuevo circovirus porcino (PCV3) en España: desarrollo de herramientas diagnósticas, asociación con enfermedad y exploración de métodos de prevención y control/ | ca |
dc.subject.udc | 619 | ca |
dc.identifier.doi | https://doi.org/10.1111/tbed.14204 | ca |
dc.contributor.group | Sanitat Animal | ca |
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