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dc.contributor.authorSaporiti, Viviane
dc.contributor.authorFranzo, Giovanni
dc.contributor.authorSibila, Marina
dc.contributor.authorSegalés, Joaquim
dc.contributor.otherProducció Animalca
dc.date.accessioned2022-01-20T13:00:44Z
dc.date.available2022-01-20T13:00:44Z
dc.date.issued2021-06-29
dc.identifier.citationSaporiti, Viviane, Giovanni Franzo, Marina Sibila, and Joaquim Segalés. 2021. "Porcine Circovirus 3 (PCV‐3) As A Causal Agent Of Disease In Swine And A Proposal Of PCV‐3 Associated Disease Case Definition". Transboundary And Emerging Diseases 68 (6): 2936-2948. doi:10.1111/tbed.14204.ca
dc.identifier.issn1865-1674ca
dc.identifier.urihttp://hdl.handle.net/20.500.12327/1500
dc.description.abstractPorcine circovirus 3 (PCV-3) was discovered in 2015 using next-generation sequencing (NGS) methods. Since then, the virus has been detected worldwide in pigs displaying several clinical-pathological outcomes as well as in healthy animals. The objective of this review is to critically discuss the evidence existing so far regarding PCV-3 as a swine pathogen. In fact, a significant number of publications claim PCV-3 as a disease causal infectious agent, but very few of them have shown strong evidence of such potential causality. The most convincing proofs of disease association are those that demonstrate a clinical picture linked to multisystemic lymphoplasmacytic to lymphohistiocytic perivascular inflammation and presence of viral nucleic acid within these lesions. Based on these evidence, individual case definitions for PCV-3-reproductive disease and PCV-3-systemic disease are proposed to standardize diagnostic criteria for PCV-3-associated diseases. However, the real frequency of these clinical-pathological conditions linked to the novel virus is unknown, and the most frequent outcome of PCV-3 infection is likely subclinical based on its worlwide distribution.ca
dc.format.extent13ca
dc.language.isoengca
dc.publisherWileyca
dc.relation.ispartofTransboundary and Emerging Diseasesca
dc.rightsAttribution-NonCommercial 4.0 Internationalca
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titlePorcine circovirus 3 (PCV-3) as a causal agent of disease in swine and a proposal of PCV-3 associated disease case definitionca
dc.typeinfo:eu-repo/semantics/articleca
dc.description.versioninfo:eu-repo/semantics/publishedVersionca
dc.rights.accessLevelinfo:eu-repo/semantics/openAccess
dc.embargo.termscapca
dc.relation.projectIDMINECO/Programa estatal de I+D+I orientada a los retos de la sociedad/E-RTA2017-00007-00-00/ES/Impacto de la infección por un nuevo circovirus porcino (PCV3) en España: desarrollo de herramientas diagnósticas, asociación con enfermedad y exploración de métodos de prevención y control/ca
dc.subject.udc619ca
dc.identifier.doihttps://doi.org/10.1111/tbed.14204ca
dc.contributor.groupSanitat Animalca


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc/4.0/
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