Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge
Wilson, Alison D.
Archibald, Allan L.
Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host’s cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vacci‑ nated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequenc‑ ing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.
619 - Veterinària
Is part of
Cortey, Martí, Gaston Arocena, Tahar Ait-Ali, Anna Vidal, Yanli Li, Gerard Martín-Valls, Alison D. Wilson, Allan L. Archibald, Enric Mateu, and Laila Darwich. 2018. "Analysis Of The Genetic Diversity And Mrna Expression Level In Porcine Reproductive And Respiratory Syndrome Virus Vaccinated Pigs That Developed Short Or Long Viremias After Challenge". Veterinary Research 49 (1). Springer Nature. doi:10.1186/s13567-018-0514-1.
Grant agreement number
MINECO/Programa Estatal de I+D+I orientada a los retos de la sociedad/AGL2014-61204-JIN/ES/Un nuevo enfoque multidisciplinario en genética de poblaciones, inmunologia y bioinformatica para comprender la inmunidad protectora en PRRSV/
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- ARTICLES CIENTÍFICS 
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